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Phenotypic Abnormality (PA): Abnormal uvea morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the eye [HP:0000478] <2>(64|78) (69|38|28)
+ 1:   Abnormal eye morphology [HP:0012372] <12>(39|48) (41|29|22)
0:   Abnormal uvea morphology [HP:0000553] <5>(7|8) (8|5|7)
- 1:   Abnormality iris morphology [HP:0000525] <14>(2|4) (3|2|0)
- 1:   Abnormal choroid morphology [HP:0000610] <6>(3|1) (4|1|2)
- 1:   Uveitis [HP:0000554] <5>(2|3) (2|1|0)
- 1:   Abnormal ciliary body morphology [HP:0012776] <2>(0|0) (0|0|0)
- 1:   Aplasia/Hypoplasia affecting the uvea [HP:0008055] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
DEATH domain0.001353Inherited
Growth factor receptor domain0.002081Inherited
Multidrug efflux transporter AcrB transmembrane domain0.00649Inherited
RNI-like0.03599Inherited
RING/U-box0.05478Inherited
gamma-Crystallin-like0.06193Inherited
Nucleotide-diphospho-sugar transferases0.2293Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Multidrug efflux transporter AcrB transmembrane domain0.001246Inherited
28-residue LRR0.001869Inherited
EGF-type module0.003143Inherited
Caspase recruitment domain, CARD0.004379Inherited
DEATH domain, DD0.04485Inherited
Crystallins/Ca-binding development proteins0.05243Inherited
PDZ domain0.05243Inherited
BCR-homology GTPase activation domain (BH-domain)0.1382Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
DEATH domain0.0007344Direct
Growth factor receptor domain0.00117Inherited
Multidrug efflux transporter AcrB transmembrane domain0.004042Inherited
EGF/Laminin0.01465Inherited
RNI-like0.02578Inherited
RING/U-box0.04073Inherited
gamma-Crystallin-like0.04665Inherited
Nucleotide-diphospho-sugar transferases0.1942Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.00006168Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.000642Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.001126Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.004042Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.00715Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00001385Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0005865Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.005698Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)