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Phenotypic Abnormality (PA): Abnormal joint morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the skeletal system [HP:0000924] <7>(88|98) (93|54|34)
+ 1:   Abnormality of skeletal morphology [HP:0011842] <17>(86|89) (90|52|33)
0:   Abnormal joint morphology [HP:0001367] <18>(19|23) (20|9|2)
- 1:   Arthritis [HP:0001369] <9>(2|2) (2|2|0)
- 1:   Joint subluxation [HP:0032153] <7>(0|0) (0|0|0)
- 1:   Synostosis of joints [HP:0100240] <7>(3|1) (3|0|0)
- 1:   Joint dislocation [HP:0001373] <6>(6|9) (7|2|0)
- 1:   Pterygium [HP:0001059] <6>(2|2) (2|1|0)
- 1:   Abnormality of lower limb joint [HP:0100491] <5>(10|13) (11|2|1)
- 1:   Abnormality of the synovia [HP:0005262] <5>(5|9) (6|2|0)
- 1:   Abnormality of upper limb joint [HP:0009810] <4>(4|5) (4|4|2)
- 1:   Abnormality of the sacroiliac joint [HP:0100781] <3>(0|0) (0|0|0)
- 1:   Arthropathy [HP:0003040] <2>(2|1) (2|0|0)
- 1:   Enlarged joints [HP:0003037] <2>(0|0) (0|0|0)
- 1:   Chondrocalcinosis [HP:0000934] <1>(0|0) (0|0|0)
- 1:   Osteochondrosis [HP:0040188] <1>(0|0) (0|0|0)
- 1:   Abnormality of mandibular symphysis [HP:3000079](0|0) (0|0|0)
- 1:   Joint hemorrhage [HP:0005261](2|2) (2|1|0)
- 1:   Joint swelling [HP:0001386](2|2) (2|0|0)
- 1:   Periarticular soft-tissue mass [HP:0020127](0|0) (0|0|0)
- 1:   Progressive joint destruction [HP:0005187](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
RuvA domain 2-like0Direct
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.04143Inherited
ARID-like0.04143Inherited
Fibrinogen C-terminal domain-like0.04979Inherited
SET domain0.05157Inherited
Tropomyosin0.06656Inherited
Restriction endonuclease-like0.0799Inherited
Hemopexin-like domain0.1063Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.1206Inherited
Nicotinic receptor ligand binding domain-like0.1206Inherited
Bromodomain0.1239Inherited
DEATH domain0.1245Inherited
Histone-fold0.1808Inherited
SNARE fusion complex0.1808Inherited
vWA-like0.1969Inherited
Cystine-knot cytokines0.2694Inherited
Trypsin-like serine proteases0.4952Inherited
Voltage-gated potassium channels0.9873Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
XPF/Rad1/Mus81 nuclease0Direct
Filamin repeat (rod domain)0Direct
Proteasome subunits0Direct
Exostosin0Direct
Fibrinogen coiled-coil and central regions0Direct
VWC domain0.004655Inherited
GLA-domain0.03339Inherited
ARID domain0.03339Inherited
Integrin A (or I) domain0.0336Inherited
Fibrinogen C-terminal domain-like0.03989Inherited
Tropomyosin0.05414Inherited
Histone lysine methyltransferases0.06196Inherited
PHD domain0.07328Inherited
Hemopexin-like domain0.09208Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.1038Inherited
Myosin rod fragments0.1038Inherited
Nicotinic receptor ligand binding domain-like0.1038Inherited
Bromodomain0.1113Inherited
Inositol polyphosphate 5-phosphatase (IPP5)0.1609Inherited
Clathrin adaptor core protein0.1609Inherited
SNARE fusion complex0.1609Inherited
RecA protein-like (ATPase-domain)0.1697Inherited
Eukaryotic proteases0.3186Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
RuvA domain 2-like0Direct
Fibrinogen coiled-coil and central regions0Direct
ARID-like0.0299Inherited
GLA-domain0.0299Inherited
Fibrinogen C-terminal domain-like0.0367Inherited
SET domain0.03814Inherited
Tropomyosin0.05041Inherited
Restriction endonuclease-like0.06155Inherited
Hemopexin-like domain0.08382Inherited
Myosin rod fragments0.09399Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.09614Inherited
Nicotinic receptor ligand binding domain-like0.09614Inherited
Bromodomain0.09911Inherited
DEATH domain0.09976Inherited
SNARE fusion complex0.1497Inherited
Histone-fold0.1497Inherited
vWA-like0.1645Inherited
Cystine-knot cytokines0.2314Inherited
Trypsin-like serine proteases0.4509Inherited
Voltage-gated potassium channels0.9655Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.003543Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.003543Inherited
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.01213Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.02492Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.09399Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.09614Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.1497Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.179Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2614Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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