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Phenotypic Abnormality (PA): Abnormality of the foot

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of limbs [HP:0040064] <8>(58|65) (63|33|25)
+ 1:   Abnormality of the lower limb [HP:0002814] <17>(31|34) (35|15|13)
0:   Abnormality of the foot [HP:0001760] <30>(20|24) (21|13|10)
- 1:   Abnormality of toe [HP:0001780] <27>(6|7) (8|4|2)
- 1:   Abnormal metatarsal morphology [HP:0001832] <23>(0|0) (0|0|0)
- 1:   Abnormality of the plantar skin of foot [HP:0100872] <13>(2|2) (2|3|0)
- 1:   Abnormality of the tarsal bones [HP:0001850] <12>(1|1) (1|1|1)
- 1:   Aplasia/Hypoplasia involving bones of the feet [HP:0006494] <8>(4|4) (5|2|3)
- 1:   Osteolysis involving bones of the feet [HP:0009134] <4>(0|0) (0|0|0)
- 1:   Abnormality of the Achilles tendon [HP:0005109] <3>(1|2) (1|1|1)
- 1:   Contractures involving the joints of the feet [HP:0008366] <3>(1|1) (1|1|1)
- 1:   Duplication involving bones of the feet [HP:0009136] <3>(1|0) (1|0|0)
- 1:   Synostosis involving bones of the feet [HP:0009140] <3>(1|0) (1|0|0)
- 1:   Abnormal foot bone ossification [HP:0010675] <2>(0|0) (0|0|0)
- 1:   Pes cavus [HP:0001761] <1>(1|1) (1|0|0)
- 1:   Positional foot deformity [HP:0005656] <1>(1|4) (1|1|0)
- 1:   Abnormality of dorsoventral patterning of the limbs [HP:0100270](0|0) (0|0|0)
- 1:   Ankylosis of feet small joints [HP:0008090](0|0) (0|0|0)
- 1:   Autoamputation of foot [HP:0001868](0|0) (0|0|0)
- 1:   Broad foot [HP:0001769](0|0) (0|0|0)
- 1:   Equinovarus deformity [HP:0008110](0|0) (0|0|0)
- 1:   Foot asymmetry [HP:0010507](0|0) (0|0|0)
- 1:   Foot osteomyelitis [HP:0001886](0|0) (0|0|0)
- 1:   Long foot [HP:0001833](0|0) (0|0|0)
- 1:   Medial deviation of the foot [HP:0008082](0|0) (0|0|0)
- 1:   Medial rotation of the medial malleolus [HP:0008132](0|0) (0|0|0)
- 1:   Narrow foot [HP:0001786](0|0) (0|0|0)
- 1:   Pes planus [HP:0001763](0|1) (0|0|0)
- 1:   Pes valgus [HP:0008081](1|1) (1|1|0)
- 1:   Podagra [HP:0001854](0|0) (0|0|0)
- 1:   Prominent subcalcaneal fat pad [HP:0032276](0|0) (0|0|0)
- 1:   Split foot [HP:0001839](0|0) (0|0|0)
- 1:   Structural foot deformity [HP:0010219](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Plakin repeat0Direct
BRK domain-like0Direct
RuvA domain 2-like0Direct
Hedgehog/intein (Hint) domain0Direct
CalX-like0Direct
Hedgehog/DD-peptidase0Direct
Rhodanese/Cell cycle control phosphatase0Direct
Arginase/deacetylase0.02839Inherited
ARID-like0.03222Inherited
WD40 repeat-like0.04616Inherited
S15/NS1 RNA-binding domain0.07175Inherited
Prefoldin0.1045Inherited
Tropomyosin0.1045Inherited
Intermediate filament protein, coiled coil region0.1297Inherited
HMG-box0.2949Inherited
Spectrin repeat0.3689Inherited
Cystine-knot cytokines0.4313Inherited
Immunoglobulin0.4353Inherited
vWA-like0.4708Inherited
Class II aaRS and biotin synthetases0.7484Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
XPF/Rad1/Mus81 nuclease0Direct
Histone deacetylase, HDAC0Direct
Hedgehog C-terminal (Hog) autoprocessing domain0Direct
Myotubularin-like phosphatases0Direct
BRK domain-like0Direct
Hedgehog (development protein), N-terminal signaling domain0Direct
Plakin repeat0Direct
CalX-beta domain0Direct
VWC domain0.00873Inherited
RecA protein-like (ATPase-domain)0.01844Inherited
ZZ domain0.0198Inherited
ARID domain0.02257Inherited
a tRNA synthase domain0.05496Inherited
Tropomyosin0.08236Inherited
Intermediate filament protein, coiled coil region0.1016Inherited
Tyrosine-dependent oxidoreductases0.1707Inherited
HMG-box0.2537Inherited
Integrin A (or I) domain0.255Inherited
I set domains0.2878Inherited
Spectrin repeat0.325Inherited
Histone lysine methyltransferases0.4184Inherited
Calponin-homology domain, CH-domain0.5198Inherited
Filamin repeat (rod domain)0.6071Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.7142Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Rhodanese/Cell cycle control phosphatase0Direct
Hedgehog/DD-peptidase0Direct
RuvA domain 2-like0Direct
Plakin repeat0Direct
BRK domain-like0Direct
CalX-like0Direct
Hedgehog/intein (Hint) domain0Direct
Arginase/deacetylase0.01983Inherited
ARID-like0.02277Inherited
WD40 repeat-like0.03373Inherited
S15/NS1 RNA-binding domain0.0548Inherited
Prefoldin0.08241Inherited
Tropomyosin0.08241Inherited
Intermediate filament protein, coiled coil region0.1044Inherited
Cysteine proteinases0.177Inherited
HMG-box0.2553Inherited
Spectrin repeat0.3263Inherited
Cystine-knot cytokines0.3874Inherited
Immunoglobulin0.3915Inherited
vWA-like0.4271Inherited
Class II aaRS and biotin synthetases0.7111Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    57581,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.01983Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.0548Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.1058Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1087Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2103Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.4184Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.4212Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    141072,141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57184,57581,57184
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57581,57184,57581
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.01983Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.09733Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2545Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.472Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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