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Phenotypic Abnormality (PA): Abnormality of the calvaria

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + + 4:   Abnormality of the skeletal system [HP:0000924] <7>(88|98) (93|55|34)
+ + + 3:   Abnormality of head or neck [HP:0000152] <2>(86|104) (97|58|38)
+ + + 3:   Abnormality of skeletal morphology [HP:0011842] <17>(86|89) (90|52|33)
+ + 2:   Abnormal axial skeleton morphology [HP:0009121] <6>(47|61) (51|30|26)
+ + 2:   Abnormality of the head [HP:0000234] <6>(85|102) (96|57|38)
+ 1:   Abnormal skull morphology [HP:0000929] <14>(25|38) (28|22|20)
0:   Abnormality of the calvaria [HP:0002683] <7>(8|15) (8|6|6)
- 1:   Abnormality of calvarial morphology [HP:0002648] <18>(3|9) (3|3|6)
- 1:   Cranial hyperostosis [HP:0004437] <4>(0|0) (0|0|0)
- 1:   Abnormality of the fontanelles or cranial sutures [HP:0000235] <2>(6|6) (6|2|1)
- 1:   Decreased calvarial ossification [HP:0005474] <1>(0|0) (0|0|0)
- 1:   Dense calvaria [HP:0000250](0|0) (0|0|0)
- 1:   Thickened calvaria [HP:0002684](0|0) (0|0|0)
- 1:   Thin calvarium [HP:0010539](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Notch domain0Direct
RuvA domain 2-like0Direct
Helical domain of Sec23/240.1218Inherited
C-terminal, gelsolin-like domain of Sec23/240.1218Inherited
Homeodomain-like0.1289Inherited
Actin-like ATPase domain0.1636Inherited
beta-sandwich domain of Sec23/240.1693Inherited
HLH, helix-loop-helix DNA-binding domain0.6328Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Protein serine/threonine phosphatase0Direct
Histone deacetylase, HDAC0Direct
Notch domain0Direct
XPF/Rad1/Mus81 nuclease0Direct
Erythroid transcription factor GATA-10.001844Inherited
RecA protein-like (ATPase-domain)0.0304Inherited
PHD domain0.05089Inherited
beta-sandwich domain of Sec23/240.1001Inherited
Trunk domain of Sec23/240.1001Inherited
C-terminal, gelsolin-like domain of Sec23/240.1001Inherited
Helical domain of Sec23/240.1001Inherited
Homeodomain0.1087Inherited
HLH, helix-loop-helix DNA-binding domain0.604Inherited
I set domains0.668Inherited
G proteins0.9048Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
RuvA domain 2-like0Direct
Notch domain0Direct
C-terminal, gelsolin-like domain of Sec23/240.09721Inherited
Helical domain of Sec23/240.09721Inherited
Homeodomain-like0.1037Inherited
Actin-like ATPase domain0.1341Inherited
beta-sandwich domain of Sec23/240.1394Inherited
HLH, helix-loop-helix DNA-binding domain0.5917Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.004205Inherited
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.09721Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.1232Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.6974Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.001868Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.008279Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1073Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.5546Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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