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Phenotypic Abnormality (PA): Abnormality of the urinary system physiology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the genitourinary system [HP:0000119] <5>(73|72) (80|28|9)
+ 1:   Abnormality of the urinary system [HP:0000079] <4>(38|41) (45|15|7)
0:   Abnormality of the urinary system physiology [HP:0011277] <3>(23|26) (28|9|5)
- 1:   Abnormality of urine homeostasis [HP:0003110] <58>(17|20) (21|7|3)
- 1:   Abnormal renal physiology [HP:0012211] <15>(9|10) (10|3|1)
- 1:   Recurrent urinary tract infections [HP:0000010] <2>(0|1) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Tricorn protease domain 20Direct
PRTase-like0Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.0005677Direct
Acyl-CoA dehydrogenase NM domain-like0.0005677Direct
PreATP-grasp domain0.005064Inherited
Glutathione synthetase ATP-binding domain-like0.0083Inherited
L-aspartase-like0.01607Inherited
4Fe-4S ferredoxins0.01607Inherited
ClpP/crotonase0.03193Inherited
Mitochondrial carrier0.08247Inherited
(Trans)glycosidases0.1177Inherited
Trypsin-like serine proteases0.1423Inherited
Complement control module/SCR domain0.1538Inherited
Transcription factor STAT-4 N-domain0.1606Inherited
STAT0.1606Inherited
Adenine nucleotide alpha hydrolases-like0.1606Inherited
Alkaline phosphatase-like0.1943Inherited
GroEL equatorial domain-like0.2317Inherited
Clc chloride channel0.2317Inherited
C-type lectin-like0.3051Inherited
TNF-like0.3436Inherited
L domain-like0.713Inherited
Cysteine-rich domain0.7566Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
beta-glycanases0Direct
Cystathionine synthase-like0Direct
HCDH C-domain-like0Direct
Phosphoribosyltransferases (PRTases)0Direct
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.00001362Direct
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.00001362Direct
BC N-terminal domain-like0.0009143Direct
Integrin alpha N-terminal domain0.0009143Direct
BC ATP-binding domain-like0.0009143Direct
Noncollagenous (NC1) domain of collagen IV0.01207Inherited
Cytoplasmic domain of inward rectifier potassium channel0.02033Inherited
Arylsulfatase0.06288Inherited
Crotonase-like0.06696Inherited
Mitochondrial carrier0.07094Inherited
Eukaryotic proteases0.1072Inherited
Complement control module/SCR domain0.1365Inherited
Transcription factor STAT-4 N-domain0.1388Inherited
STAT DNA-binding domain0.1388Inherited
RecA protein-like (ATPase-domain)0.1388Inherited
STAT0.1388Inherited
Cytochrome P4500.1741Inherited
Clc chloride channel0.2052Inherited
TNF-like0.3181Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.596Inherited
Ngr ectodomain-like0.6616Inherited
Voltage-gated potassium channels0.8984Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Tricorn protease domain 20Direct
PRTase-like0Direct
Acyl-CoA dehydrogenase NM domain-like0.0002892Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.0002892Direct
Integrin domains0.003081Inherited
PreATP-grasp domain0.003081Inherited
Glutathione synthetase ATP-binding domain-like0.005272Inherited
L-aspartase-like0.01072Inherited
4Fe-4S ferredoxins0.01072Inherited
ClpP/crotonase0.02252Inherited
Mitochondrial carrier0.0637Inherited
CBS-domain pair0.0871Inherited
(Trans)glycosidases0.09362Inherited
Trypsin-like serine proteases0.1157Inherited
Complement control module/SCR domain0.1258Inherited
Adenine nucleotide alpha hydrolases-like0.1316Inherited
Transcription factor STAT-4 N-domain0.1316Inherited
STAT0.1316Inherited
Cytochrome P4500.162Inherited
Alkaline phosphatase-like0.162Inherited
GroEL equatorial domain-like0.1964Inherited
Clc chloride channel0.1964Inherited
C-type lectin-like0.2651Inherited
TNF-like0.3021Inherited
E set domains0.4485Inherited
L domain-like0.6744Inherited
Cysteine-rich domain0.7197Inherited
Voltage-gated potassium channels0.9783Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.0002892Direct
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.0007886Direct
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.0007886Direct
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.01847Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.04434Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.0637Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.1316Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.1316Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.1316Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.0007886Direct
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.0007886Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.007097Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.1316Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.1316Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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