SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Phenotypic Abnormality (PA): Abnormal renal physiology

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the genitourinary system [HP:0000119] <5>(73|72) (80|28|9)
+ + 2:   Abnormality of the upper urinary tract [HP:0010935] <2>(21|22) (22|7|3)
+ + 2:   Abnormality of the urinary system [HP:0000079] <4>(38|41) (45|15|7)
+ 1:   Abnormality of the urinary system physiology [HP:0011277] <3>(23|26) (28|9|5)
+ 1:   Abnormality of the kidney [HP:0000077] <3>(17|16) (18|6|3)
0:   Abnormal renal physiology [HP:0012211] <15>(9|10) (10|3|1)
- 1:   Abnormality of renal resorption [HP:0011038] <4>(0|0) (0|0|0)
- 1:   Nephrotic syndrome [HP:0000100] <4>(1|0) (1|0|0)
- 1:   Renal tubular dysfunction [HP:0000124] <4>(1|0) (1|0|0)
- 1:   Abnormality of renal excretion [HP:0011036] <3>(2|4) (3|2|1)
- 1:   Nephritis [HP:0000123] <3>(2|3) (2|1|0)
- 1:   Renal insufficiency [HP:0000083] <3>(2|3) (2|2|1)
- 1:   Abnormal glomerular filtration rate [HP:0012212] <2>(0|0) (0|0|0)
- 1:   Hematuria [HP:0000790] <2>(1|3) (1|1|0)
- 1:   Elevated alkaline phosphatase of renal origin [HP:0010680](0|0) (0|0|0)
- 1:   Hemolytic-uremic syndrome [HP:0005575](1|1) (1|1|1)
- 1:   Impaired urinary acidification [HP:0031033](0|0) (0|0|0)
- 1:   Isothenuria [HP:0030036](0|0) (0|0|0)
- 1:   Low alkaline phosphatase of renal origin [HP:0010685](0|0) (0|0|0)
- 1:   Nephropathy [HP:0000112](0|0) (0|0|0)
- 1:   Renovascular hypertension [HP:0100817](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Tricorn protease domain 20Direct
PRTase-like0Direct
4Fe-4S ferredoxins0.004135Inherited
GroEL equatorial domain-like0.01291Inherited
Trypsin-like serine proteases0.02521Inherited
Complement control module/SCR domain0.02695Inherited
TNF-like0.1263Inherited
Cysteine-rich domain0.522Inherited
L domain-like0.5288Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Phosphoribosyltransferases (PRTases)0Direct
Noncollagenous (NC1) domain of collagen IV0.001966Inherited
Eukaryotic proteases0.006594Inherited
Complement control module/SCR domain0.01966Inherited
Cytoplasmic domain of inward rectifier potassium channel0.0515Inherited
Cystathionine synthase-like0.09436Inherited
TNF-like0.1046Inherited
Ngr ectodomain-like0.3036Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.3484Inherited
Voltage-gated potassium channels0.6856Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Tricorn protease domain 20Direct
PRTase-like0Direct
4Fe-4S ferredoxins0.002469Inherited
GroEL equatorial domain-like0.008488Inherited
Trypsin-like serine proteases0.01745Inherited
Complement control module/SCR domain0.01873Inherited
TNF-like0.1013Inherited
E set domains0.3317Inherited
Cysteine-rich domain0.4775Inherited
L domain-like0.4845Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.007736Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.00953Inherited
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.05156Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.0006027Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)