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Mode of Inheritance (MI): Autosomal dominant inheritance

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   Mode of inheritance [HP:0000005] <12>
0:   Autosomal dominant inheritance [HP:0000006] <6>(25|32) (27|26|14)
- 1:   Sex-limited autosomal dominant [HP:0001470] <1>(0|0) (0|0|0)
- 1:   Autosomal dominant contiguous gene syndrome [HP:0001452](0|0) (0|0|0)
- 1:   Autosomal dominant germline de novo mutation [HP:0025352](0|0) (0|0|0)
- 1:   Autosomal dominant inheritance with maternal imprinting [HP:0012275](0|0) (0|0|0)
- 1:   Autosomal dominant inheritance with paternal imprinting [HP:0012274](0|0) (0|0|0)
- 1:   Autosomal dominant somatic cell mutation [HP:0001444](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Translation proteins SH3-like domain0Direct
Sm-like ribonucleoproteins0Direct
Myosin rod fragments0Direct
Globin-like0Direct
Tropomyosin0Direct
HSP20-like chaperones0Direct
Lamin A/C globular tail domain0Direct
Connexin430Direct
Hormone receptor domain0Direct
Sema domain0Direct
gamma-Crystallin-like0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
NTF2-like0Direct
Apolipoprotein A-I0Direct
Aquaporin-like0Direct
BRK domain-like0Direct
Intermediate filament protein, coiled coil region0.00000000002034Direct
Voltage-gated potassium channels0.00000002421Direct
Homeodomain-like0.00001132Direct
Tubulin nucleotide-binding domain-like0.0000589Direct
Tubulin C-terminal domain-like0.0001246Direct
Neurotransmitter-gated ion-channel transmembrane pore0.000232Direct
Nicotinic receptor ligand binding domain-like0.000232Direct
Protein kinase-like (PK-like)0.0003038Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0007206Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
HkH motif-containing C2H2 finger0Direct
Sema domain0Direct
Protein serine/threonine phosphatase0Direct
Globins0Direct
DNA gyrase/MutL, second domain0Direct
Lamin A/C globular tail domain0Direct
Apolipoprotein A-I0Direct
p120GAP domain-like0Direct
Crystallins/Ca-binding development proteins0Direct
BRK domain-like0Direct
Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A0Direct
Myosin rod fragments0Direct
Aquaporin-like0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
Tropomyosin0Direct
ets domain0Direct
CUT domain0Direct
Histone lysine methyltransferases0Direct
Hormone receptor domain0Direct
DIX domain0Direct
Connexin430Direct
DEP domain0Direct
DNA gyrase/MutL, N-terminal domain0Direct
L domain0Direct
Intermediate filament protein, coiled coil region0.00000000005308Direct
Voltage-gated potassium channels0.00002841Direct
Tubulin, GTPase domain0.00007487Direct
Tubulin, C-terminal domain0.0001565Direct
Neurotransmitter-gated ion-channel transmembrane pore0.000314Direct
Nicotinic receptor ligand binding domain-like0.000314Direct
Protein kinases, catalytic subunit0.000375Direct
Homeodomain0.0005196Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Sm-like ribonucleoproteins0Direct
BRK domain-like0Direct
Connexin430Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
Myosin rod fragments0Direct
Apolipoprotein A-I0Direct
Tropomyosin0Direct
Sema domain0Direct
Translation proteins SH3-like domain0Direct
gamma-Crystallin-like0Direct
Lamin A/C globular tail domain0Direct
Aquaporin-like0Direct
Hormone receptor domain0Direct
HSP20-like chaperones0Direct
Globin-like0Direct
NTF2-like0Direct
Intermediate filament protein, coiled coil region0.00000000001416Direct
Voltage-gated potassium channels0.00000001698Direct
Homeodomain-like0.000008064Direct
Tubulin nucleotide-binding domain-like0.00004229Direct
Tubulin C-terminal domain-like0.00009061Direct
Nicotinic receptor ligand binding domain-like0.0001753Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0001753Direct
Protein kinase-like (PK-like)0.00023Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0005645Direct
SET domain0.0008564Direct
HMG-box0.0008689Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46689,57667
  • 46689 - Homeodomain-like
  • 57667 - beta-beta-alpha zinc fingers
  • 0Direct
    46966,47473
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0Direct
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0Direct
    47454,57959
  • 47454 - A DNA-binding domain in eukaryotic transcription factors
  • 57959 - Leucine zipper domain
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0Direct
    57581,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    81324,81324
  • 81324 - Voltage-gated potassium channels
  • 81324 - Voltage-gated potassium channels
  • 0Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.00009061Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0001753Direct
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.0005317Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    90257,90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0Direct
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0Direct
    46966,46966,47473
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0Direct
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57184,57581,57184
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57581,57184,57581
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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