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Phenotypic Abnormality (PA): Hearing impairment

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the ear [HP:0000598] <2>(17|32) (21|13|11)
+ + 2:   Abnormal ear physiology [HP:0031704] <2>(7|10) (9|4|7)
+ 1:   Hearing abnormality [HP:0000364] <3>(7|10) (9|4|7)
0:   Hearing impairment [HP:0000365] <13>(7|10) (9|4|7)
- 1:   Sensorineural hearing impairment [HP:0000407] <13>(4|3) (5|1|1)
- 1:   Conductive hearing impairment [HP:0000405] <8>(1|0) (1|0|4)
- 1:   Mild hearing impairment [HP:0012712] <4>(0|0) (0|0|0)
- 1:   Moderate hearing impairment [HP:0012713] <2>(0|0) (1|0|0)
- 1:   Severe hearing impairment [HP:0012714] <2>(0|0) (0|0|0)
- 1:   Profound hearing impairment [HP:0012715] <1>(0|0) (0|0|0)
- 1:   Progressive hearing impairment [HP:0001730] <1>(0|0) (0|0|0)
- 1:   Aminoglycoside-induced hearing loss [HP:0011975](0|0) (0|0|0)
- 1:   High-frequency hearing impairment [HP:0005101](0|0) (0|0|0)
- 1:   Low-frequency hearing loss [HP:0008542](0|0) (0|0|0)
- 1:   Mid-frequency hearing loss [HP:0012781](0|0) (0|0|0)
- 1:   Transient hearing impairment [HP:0012779](0|0) (0|0|0)
- 1:   Unilateral deafness [HP:0009900](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
L27 domain0Direct
Lamin A/C globular tail domain0Direct
ADC-like0Direct
Smc hinge domain0Direct
SET domain0.02492Inherited
Integrin domains0.1961Inherited
Family A G protein-coupled receptor-like0.8547Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
beta-glycanases0Direct
L27 domain0Direct
Lamin A/C globular tail domain0Direct
Lipoxigenase N-terminal domain0Direct
Smc hinge domain0Direct
XPF/Rad1/Mus81 nuclease0Direct
Extended AAA-ATPase domain0.0004456Direct
Arylsulfatase0.0007384Direct
Integrin domains0.1588Inherited
Rhodopsin-like0.7893Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Smc hinge domain0Direct
Lamin A/C globular tail domain0Direct
ADC-like0Direct
L27 domain0Direct
PDZ domain-like0.0009056Direct
SET domain0.01723Inherited
Integrin domains0.1637Inherited
Cysteine proteinases0.6077Inherited
Family A G protein-coupled receptor-like0.8225Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0Direct
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0Direct
    141072,141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.02684Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.06676Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1117Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.135Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)