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Phenotypic Abnormality (PA): Abnormality of the thyroid gland

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of the endocrine system [HP:0000818] <16>(30|34) (35|12|5)
0:   Abnormality of the thyroid gland [HP:0000820] <2>(8|7) (8|3|0)
- 1:   Abnormality of thyroid physiology [HP:0002926] <9>(1|1) (2|0|0)
- 1:   Abnormality of thyroid morphology [HP:0011772] <8>(7|6) (7|3|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.02216Inherited
Homeodomain-like0.02419Inherited
DNA repair protein MutS, domain III0.04923Inherited
SAND domain-like0.04923Inherited
Ribosomal protein S5 domain 2-like0.05087Inherited
Sema domain0.06117Inherited
Plexin repeat0.1798Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.2113Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
DNA gyrase/MutL, second domain0.00007615Direct
DNA gyrase/MutL, N-terminal domain0.00007615Direct
DNA repair protein MutS, domain III0.04402Inherited
Homeodomain0.04659Inherited
Sema domain0.05719Inherited
Plexin repeat0.1765Inherited
PLC-like (P variant)0.1943Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.01535Inherited
Homeodomain-like0.01683Inherited
SAND domain-like0.0366Inherited
DNA repair protein MutS, domain III0.0366Inherited
Ribosomal protein S5 domain 2-like0.03793Inherited
Sema domain0.04639Inherited
Plexin repeat0.1494Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.1784Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.00004825Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0366Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.04639Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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