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Phenotypic Abnormality (PA): Abnormality of the metaphysis

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the skeletal system [HP:0000924] <7>(89|98) (94|51|33)
+ + + 3:   Abnormality of limbs [HP:0040064] <8>(57|64) (59|32|25)
+ + + 3:   Abnormality of skeletal morphology [HP:0011842] <18>(87|89) (90|49|32)
+ + 2:   Abnormality of limb bone [HP:0040068] <1>(28|30) (30|18|20)
+ + 2:   Abnormal appendicular skeleton morphology [HP:0011844] <4>(35|41) (38|23|23)
+ 1:   Abnormality of long bone morphology [HP:0011314] <18>(6|9) (6|3|1)
+ 1:   Abnormality of limb bone morphology [HP:0002813] <13>(28|30) (30|18|20)
0:   Abnormality of the metaphysis [HP:0000944] <19>(2|5) (2|1|0)
- 1:   Abnormality of upper limb metaphysis [HP:0009809] <12>(0|0) (0|0|0)
- 1:   Metaphyseal enchondromatosis [HP:0005868] <5>(0|0) (0|0|0)
- 1:   Metaphyseal widening [HP:0003016] <4>(2|3) (2|1|0)
- 1:   Metaphyseal cupping [HP:0003021] <3>(0|0) (0|0|0)
- 1:   Metaphyseal irregularity [HP:0003025] <3>(0|0) (0|0|0)
- 1:   Abnormality of lower-limb metaphyses [HP:0006490] <2>(0|0) (0|0|0)
- 1:   Metaphyseal sclerosis [HP:0004979] <2>(0|0) (0|0|0)
- 1:   Metaphyseal striations [HP:0031367] <2>(0|0) (0|0|0)
- 1:   Abnormal metaphyseal trabeculation [HP:0005089] <1>(0|0) (0|0|0)
- 1:   Enlarged metaphyses [HP:0003051] <1>(0|0) (0|0|0)
- 1:   Metaphyseal dysplasia [HP:0100255] <1>(0|0) (0|0|0)
- 1:   Metaphyseal spurs [HP:0005054] <1>(0|0) (0|0|0)
- 1:   Abnormal metaphyseal vascular invasion [HP:0003562](0|0) (0|0|0)
- 1:   Alternating radiolucent and radiodense metaphyseal lines [HP:0031016](0|0) (0|0|0)
- 1:   Corner fracture of metaphysis [HP:0003908](0|0) (0|0|0)
- 1:   Dense metaphyseal bands [HP:0100959](0|0) (0|0|0)
- 1:   Dumbbell-shaped metaphyses [HP:0002810](0|0) (0|0|0)
- 1:   Metaphyseal dysostosis [HP:0005899](0|0) (0|0|0)
- 1:   Metaphyseal rarefaction [HP:0004980](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PGBD-like0.004875Inherited
Hemopexin-like domain0.01501Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Exostosin0Direct
Fibronectin type II module0.0001805Direct
Matrix metalloproteases, catalytic domain0.00328Inherited
MMP N-terminal domain0.00328Inherited
Hemopexin-like domain0.01084Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PGBD-like0.003001Inherited
Hemopexin-like domain0.01008Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.003001Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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