SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Phenotypic Abnormality (PA): Thickened skin

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the integument [HP:0001574] <4>(48|69) (59|37|15)
+ + 2:   Abnormality of the skin [HP:0000951] <4>(34|55) (45|36|12)
+ 1:   Abnormality of skin morphology [HP:0011121] <22>(29|49) (40|31|11)
0:   Thickened skin [HP:0001072] <4>(3|6) (3|6|2)
- 1:   Epidermal thickening [HP:0011368] <9>(3|6) (3|6|2)
- 1:   Scleroderma [HP:0100324] <1>(0|0) (0|0|0)
- 1:   Morphea [HP:0012344](0|0) (0|0|0)
- 1:   Sclerodactyly [HP:0011838](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Intermediate filament protein, coiled coil region0.0000008946Direct
Spectrin repeat0.01015Inherited
Prefoldin0.06512Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Intermediate filament protein, coiled coil region0.00000042Direct
Integrin A (or I) domain0.004635Inherited
Spectrin repeat0.006643Inherited
Ras-binding domain, RBD0.018Inherited
Laminin-type module0.04324Inherited
Tyrosine-dependent oxidoreductases0.0867Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Intermediate filament protein, coiled coil region0.0000003546Direct
Spectrin repeat0.006541Inherited
Prefoldin0.04926Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49265,53300
  • 49265 - Fibronectin type III
  • 53300 - vWA-like
  • 0Direct
    53300,49265
  • 53300 - vWA-like
  • 49265 - Fibronectin type III
  • 0Direct
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.002559Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.01763Inherited
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.01763Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.03259Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49265,49265,53300
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 53300 - vWA-like
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.005833Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)