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Phenotypic Abnormality (PA): Seizures

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the nervous system [HP:0000707] <4>(147|170) (164|102|45)
+ 1:   Abnormality of nervous system physiology [HP:0012638] <26>(104|120) (119|81|38)
0:   Seizures [HP:0001250] <8>(12|14) (12|5|1)
- 1:   Focal-onset seizure [HP:0007359] <7>(0|0) (0|0|0)
- 1:   Generalized-onset seizure [HP:0002197] <6>(3|3) (3|2|0)
- 1:   Febrile seizures [HP:0002373] <2>(1|3) (1|0|0)
- 1:   Status epilepticus [HP:0002133] <2>(1|2) (1|0|0)
- 1:   Symptomatic seizures [HP:0011145] <2>(0|0) (0|0|0)
- 1:   Epileptic spasms [HP:0011097] <1>(0|0) (0|0|0)
- 1:   Multifocal seizures [HP:0031165](0|0) (0|0|0)
- 1:   Nocturnal seizures [HP:0031951](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SNARE fusion complex0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
BRK domain-like0Direct
ADC-like0Direct
CCCH zinc finger0Direct
Methylglyoxal synthase-like0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Acyl-CoA N-acyltransferases (Nat)0Direct
Voltage-gated potassium channels0.005781Inherited
Nicotinic receptor ligand binding domain-like0.2141Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.2141Inherited
KRAB domain (Kruppel-associated box)0.2555Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Ferredoxin domains from multidomain proteins0Direct
Glycosyl transferases group 10Direct
CCCH zinc finger0Direct
IF2B-like0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
N-acetyl transferase, NAT0Direct
SNARE fusion complex0Direct
L-aspartase/fumarase0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
BRK domain-like0Direct
Nicotinic receptor ligand binding domain-like0.1825Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.1825Inherited
KRAB domain (Kruppel-associated box)0.2179Inherited
Nucleotide and nucleoside kinases0.4955Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
BRK domain-like0Direct
ADC-like0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Acyl-CoA N-acyltransferases (Nat)0Direct
CCCH zinc finger0Direct
Methylglyoxal synthase-like0Direct
SNARE fusion complex0Direct
Voltage-gated potassium channels0.003613Inherited
Nicotinic receptor ligand binding domain-like0.181Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.181Inherited
KRAB domain (Kruppel-associated box)0.2193Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0Direct
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.181Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2193Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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