SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Phenotypic Abnormality (PA): Ataxia

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Phenotypic abnormality [HP:0000118] <25>
+ + + + 4:   Abnormality of the nervous system [HP:0000707] <4>(142|168) (156|103|45)
+ + + 3:   Abnormality of nervous system physiology [HP:0012638] <26>(101|119) (112|81|39)
+ + 2:   Abnormality of central motor function [HP:0011442] <10>(22|26) (30|16|7)
+ 1:   Abnormality of coordination [HP:0011443] <5>(2|3) (7|5|2)
0:   Ataxia [HP:0001251] <11>(2|2) (7|4|2)
- 1:   Dyssynergia [HP:0010867] <2>(0|0) (0|0|0)
- 1:   Gait ataxia [HP:0002066] <2>(0|0) (0|0|0)
- 1:   Dysmetria [HP:0001310] <1>(0|0) (1|0|0)
- 1:   Truncal ataxia [HP:0002078] <1>(0|0) (3|2|1)
- 1:   Cerebellar ataxia associated with quadrupedal gait [HP:0009878](0|0) (0|0|0)
- 1:   Dysdiadochokinesis [HP:0002075](0|0) (0|0|0)
- 1:   Episodic ataxia [HP:0002131](0|1) (1|0|0)
- 1:   Limb ataxia [HP:0002070](0|0) (0|0|0)
- 1:   Nonprogressive cerebellar ataxia [HP:0002470](0|0) (0|0|0)
- 1:   Progressive cerebellar ataxia [HP:0002073](0|0) (0|0|0)
- 1:   Spastic ataxia [HP:0002497](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
CRAL/TRIO domain0.0007097Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Extended AAA-ATPase domain0.0001582Direct
Nucleotide and nucleoside kinases0.1426Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
CRAL/TRIO domain0.0003666Direct
Metal cation-transporting ATPase, ATP-binding domain N0.05913Inherited
BRCT domain0.1403Inherited
HAD-like0.4728Inherited
Calcium ATPase, transduction domain A0.6052Inherited
Calcium ATPase, transmembrane domain M0.6052Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47005,52777
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    51230,47005
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 0Direct
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.0425Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.05913Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    51230,47005,52777
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.05913Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)