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Phenotypic Abnormality (PA): Spasticity

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Abnormality of the nervous system [HP:0000707] <4>(142|168) (156|103|45)
+ + + + + 5:   Phenotypic abnormality [HP:0000118] <25>
+ + + + 4:   Abnormality of the musculature [HP:0003011] <3>(64|83) (70|33|9)
+ + + + 4:   Abnormality of nervous system physiology [HP:0012638] <26>(101|119) (112|81|39)
+ + + 3:   Abnormality of central motor function [HP:0011442] <10>(22|26) (30|16|7)
+ + + 3:   Abnormal muscle physiology [HP:0011804] <12>(44|59) (51|22|5)
+ + 2:   Upper motor neuron dysfunction [HP:0002493] <4>(9|15) (13|8|4)
+ + 2:   Abnormal muscle tone [HP:0003808] <3>(23|37) (27|15|5)
+ 1:   Hypertonia [HP:0001276] <3>(4|9) (5|5|2)
0:   Spasticity [HP:0001257] <13>(3|6) (3|3|2)
- 1:   Lower limb spasticity [HP:0002061] <2>(0|0) (0|0|0)
- 1:   Spastic gait [HP:0002064] <2>(0|0) (0|0|0)
- 1:   Progressive spasticity [HP:0002191] <1>(0|0) (0|0|0)
- 1:   Clasp-knife sign [HP:0031866](0|0) (0|0|0)
- 1:   Opisthotonus [HP:0002179](0|0) (0|0|0)
- 1:   Spastic diplegia [HP:0001264](0|0) (0|0|0)
- 1:   Spastic dysarthria [HP:0002464](0|0) (0|0|0)
- 1:   Spastic hemiparesis [HP:0011099](0|0) (0|0|0)
- 1:   Spastic tetraparesis [HP:0001285](0|0) (0|0|0)
- 1:   Spastic tetraplegia [HP:0002510](0|0) (0|0|0)
- 1:   Spasticity of facial muscles [HP:0002491](0|0) (0|0|0)
- 1:   Spasticity of pharyngeal muscles [HP:0002501](0|0) (0|0|0)
- 1:   Upper limb spasticity [HP:0006986](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
ADC-like0Direct
Translation proteins0.0001848Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
IF2B-like0Direct
UBA domain0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Serum paraoxonase/arylesterase 1, PON10Direct
Extended AAA-ATPase domain0.00005108Direct
Elongation factors0.0006533Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
ADC-like0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Translation proteins0.00008812Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    50447,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.00005033Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)