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Phenotypic Abnormality (PA): Flexion contracture

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Abnormality of the skeletal system [HP:0000924] <7>(89|98) (94|51|33)
+ + 2:   Abnormality of skeletal physiology [HP:0011843] <8>(16|23) (18|15|15)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the musculature [HP:0003011] <3>(62|74) (69|31|7)
+ + 2:   Abnormality of skeletal morphology [HP:0011842] <18>(87|89) (90|49|32)
+ 1:   Abnormal skeletal muscle morphology [HP:0011805] <38>(30|34) (32|13|3)
+ 1:   Abnormality of joint mobility [HP:0011729] <6>(15|21) (17|15|15)
+ 1:   Abnormal tendon morphology [HP:0100261] <8>(7|10) (7|7|1)
+ 1:   Abnormality of connective tissue [HP:0003549] <12>(18|25) (18|18|19)
0:   Flexion contracture [HP:0001371] <9>(7|10) (7|7|1)
- 1:   Congenital contracture [HP:0002803] <5>(1|1) (1|1|0)
- 1:   Flexion contracture of digit [HP:0030044] <3>(0|1) (0|3|0)
- 1:   Limb joint contracture [HP:0003121] <2>(5|4) (5|4|1)
- 1:   Joint contractures involving the joints of the feet [HP:0100492] <1>(0|0) (0|0|0)
- 1:   Contractures of the large joints [HP:0005781](0|0) (0|0|0)
- 1:   Decreased cervical spine flexion due to contractures of posterior cervical muscles [HP:0004631](2|2) (2|1|1)
- 1:   Multiple joint contractures [HP:0002828](1|1) (1|1|0)
- 1:   Progressive flexion contractures [HP:0005876](0|0) (0|0|0)
- 1:   Restricted neck movement due to contractures [HP:0005997](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Ribonuclease PH domain 2-like0Direct
Spectrin repeat0.02547Inherited
Tropomyosin0.02655Inherited
MIR domain0.04802Inherited
vWA-like0.06764Inherited
Troponin coil-coiled subunits0.1078Inherited
Calponin-homology domain, CH-domain0.1089Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
Ribonuclease PH domain 1-like0Direct
Ribonuclease PH domain 2-like0Direct
DNA gyrase/MutL, second domain0.0005387Direct
DNA gyrase/MutL, N-terminal domain0.0005387Direct
Integrin A (or I) domain0.002188Inherited
Spectrin repeat0.01721Inherited
Tropomyosin0.01832Inherited
MIR domain0.0353Inherited
Calponin-homology domain, CH-domain0.08591Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Ribonuclease PH domain 2-like0Direct
Spectrin repeat0.01776Inherited
Tropomyosin0.01858Inherited
MIR domain0.0356Inherited
vWA-like0.05167Inherited
Troponin coil-coiled subunits0.08555Inherited
Calponin-homology domain, CH-domain0.08651Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0005359Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.008462Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.009717Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.01313Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.0356Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.05546Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.008043Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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