SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Phenotypic Abnormality (PA): Joint hypermobility

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the skeletal system [HP:0000924] <7>(89|98) (94|51|33)
+ + 2:   Abnormality of skeletal physiology [HP:0011843] <8>(16|23) (18|15|15)
+ 1:   Abnormality of joint mobility [HP:0011729] <6>(15|21) (17|15|15)
0:   Joint hypermobility [HP:0001382] <8>(5|9) (5|3|1)
- 1:   Finger joint hypermobility [HP:0006094] <2>(1|1) (1|1|0)
- 1:   Hyperextensible hand joints [HP:0005639] <1>(0|0) (0|0|0)
- 1:   Hypermobility of interphalangeal joints [HP:0005620] <1>(0|0) (0|0|0)
- 1:   Hip joint hypermobility [HP:0045087](0|0) (0|0|0)
- 1:   Hyperextensibility at elbow [HP:0010485](0|0) (0|0|0)
- 1:   Hyperextensibility at wrists [HP:0005072](1|1) (1|1|0)
- 1:   Joint hyperflexibility [HP:0005692](3|7) (3|2|1)
- 1:   Knee joint hypermobility [HP:0045086](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
C-terminal, gelsolin-like domain of Sec23/240.0003028Direct
Helical domain of Sec23/240.0003028Direct
Bromodomain0.0005318Direct
vWA-like0.0141Inherited
ARID-like0.03208Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
beta-sandwich domain of Sec23/240.0001991Direct
C-terminal, gelsolin-like domain of Sec23/240.0001991Direct
Trunk domain of Sec23/240.0001991Direct
Helical domain of Sec23/240.0001991Direct
Bromodomain0.0004006Direct
VWC domain0.009885Inherited
Ras-binding domain, RBD0.02633Inherited
ARID domain0.02633Inherited
Integrin A (or I) domain0.09079Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
C-terminal, gelsolin-like domain of Sec23/240.0001537Direct
Helical domain of Sec23/240.0001537Direct
Bromodomain0.0002771Direct
vWA-like0.009434Inherited
ARID-like0.02288Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0001537Direct
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.0006286Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.05606Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.02288Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)