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Phenotypic Abnormality (PA): Abnormality of the liver

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the digestive system [HP:0025031] <6>(63|72) (76|45|24)
+ 1:   Abnormality of the abdominal organs [HP:0002012] <6>(26|24) (29|11|3)
0:   Abnormality of the liver [HP:0001392] <4>(16|11) (17|6|0)
- 1:   Abnormal liver morphology [HP:0410042] <25>(13|8) (13|4|0)
- 1:   Abnormality of the biliary system [HP:0004297] <5>(1|0) (2|1|0)
- 1:   Neoplasm of the liver [HP:0002896] <4>(2|2) (2|1|0)
- 1:   Abnormal liver physiology [HP:0031865] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Glycosyl hydrolase domain0.0005437Direct
(Trans)glycosidases0.0006794Direct
Globin-like0.001424Inherited
Ribosomal protein S5 domain 2-like0.007466Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.01954Inherited
Acyl-CoA dehydrogenase NM domain-like0.01954Inherited
Adenine nucleotide alpha hydrolases-like0.03454Inherited
GroEL equatorial domain-like0.04325Inherited
ABC transporter transmembrane region0.08715Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like0.1244Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1247Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.1635Inherited
Nucleotidylyl transferase0.269Inherited
SH3-domain0.4399Inherited
WD40 repeat-like0.6955Inherited
TPR-like0.8923Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
Subtilases0Direct
Putative glucosidase YicI, domain 30Direct
Globins0.0008983Direct
DNA gyrase/MutL, second domain0.003298Inherited
DNA gyrase/MutL, N-terminal domain0.003298Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.0201Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.0201Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.1217Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.2529Inherited
SH3-domain0.3979Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Glycosyl hydrolase domain0.0002838Direct
(Trans)glycosidases0.0003583Direct
Globin-like0.0007945Direct
UDP-Glycosyltransferase/glycogen phosphorylase0.0008331Direct
Ribosomal protein S5 domain 2-like0.004775Inherited
Acyl-CoA dehydrogenase NM domain-like0.01339Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.01339Inherited
Adenine nucleotide alpha hydrolases-like0.02479Inherited
GroEL equatorial domain-like0.03169Inherited
ABC transporter transmembrane region0.06796Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like0.1001Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1004Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.135Inherited
Nucleotidylyl transferase0.2324Inherited
SH3-domain0.397Inherited
WD40 repeat-like0.6575Inherited
TPR-like0.8628Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0.0002838Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.002998Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.01339Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.06796Inherited
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.1001Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.1915Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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