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Phenotypic Abnormality (PA): Abnormality of the liver

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the digestive system [HP:0025031] <6>(67|77) (77|47|25)
+ 1:   Abnormality of the abdominal organs [HP:0002012] <6>(27|27) (30|14|4)
0:   Abnormality of the liver [HP:0001392] <4>(17|12) (17|7|0)
- 1:   Abnormal liver morphology [HP:0410042] <25>(13|9) (13|4|0)
- 1:   Abnormality of the biliary system [HP:0004297] <5>(1|1) (2|1|0)
- 1:   Neoplasm of the liver [HP:0002896] <4>(2|2) (2|1|0)
- 1:   Abnormal liver physiology [HP:0031865] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
UDP-Glycosyltransferase/glycogen phosphorylase0.0001864Direct
Glycosyl hydrolase domain0.0005974Direct
(Trans)glycosidases0.0007723Direct
Globin-like0.001528Inherited
Ribosomal protein S5 domain 2-like0.01281Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.02061Inherited
Acyl-CoA dehydrogenase NM domain-like0.02061Inherited
Adenine nucleotide alpha hydrolases-like0.03591Inherited
GroEL equatorial domain-like0.04478Inherited
ABC transporter transmembrane region0.09099Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like0.1279Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1287Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.1691Inherited
Nucleotidylyl transferase0.315Inherited
SH3-domain0.506Inherited
WD40 repeat-like0.7124Inherited
TPR-like0.9006Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
Glycosyl transferases group 10Direct
Putative glucosidase YicI, domain 30Direct
Globins0.0009945Direct
DNA gyrase/MutL, second domain0.003587Inherited
DNA gyrase/MutL, N-terminal domain0.003587Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.02167Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.02167Inherited
ABC transporter transmembrane region0.08104Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.1587Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.2627Inherited
SH3-domain0.4742Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
UDP-Glycosyltransferase/glycogen phosphorylase0.00008866Direct
Glycosyl hydrolase domain0.0003054Direct
(Trans)glycosidases0.0004013Direct
Globin-like0.0008361Direct
Ribosomal protein S5 domain 2-like0.008403Inherited
Acyl-CoA dehydrogenase NM domain-like0.01408Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.01408Inherited
Adenine nucleotide alpha hydrolases-like0.02569Inherited
GroEL equatorial domain-like0.03259Inherited
ABC transporter transmembrane region0.07085Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like0.1027Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1035Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.1392Inherited
Nucleotidylyl transferase0.2744Inherited
SH3-domain0.4617Inherited
WD40 repeat-like0.6737Inherited
TPR-like0.8713Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
103473,100895
  • 103473 - MFS general substrate transporter
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0.0003054Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.003132Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.01408Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.07085Inherited
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.1027Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.1959Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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