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Phenotypic Abnormality (PA): Abnormal thrombocyte morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of blood and blood-forming tissues [HP:0001871] <11>(22|35) (29|15|5)
0:   Abnormal thrombocyte morphology [HP:0001872] <4>(7|11) (8|7|4)
- 1:   Abnormal platelet function [HP:0011869] <6>(1|1) (1|0|0)
- 1:   Abnormal platelet morphology [HP:0011875] <5>(0|0) (0|0|0)
- 1:   Abnormal platelet count [HP:0011873] <2>(6|9) (6|7|4)
- 1:   Abnormal platelet volume [HP:0011876] <2>(1|1) (1|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Ras GEF0.000106Direct
Transcription factor STAT-4 N-domain0.0004786Direct
STAT0.0004786Direct
SH2 domain0.007138Inherited
Complement control module/SCR domain0.01576Inherited
Integrin domains0.04593Inherited
L domain-like0.6464Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
Ras GEF0.00006135Direct
STAT DNA-binding domain0.0002879Direct
STAT0.0002879Direct
Transcription factor STAT-4 N-domain0.0002879Direct
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.0003834Direct
SH2 domain0.00417Inherited
Complement control module/SCR domain0.01008Inherited
Integrin domains0.0333Inherited
Ngr ectodomain-like0.2317Inherited
DEATH domain, DD0.3147Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Ras GEF0.0000508Direct
Transcription factor STAT-4 N-domain0.0002482Direct
STAT0.0002482Direct
p53-like transcription factors0.0006989Direct
SH2 domain0.004546Inherited
Complement control module/SCR domain0.01061Inherited
Integrin domains0.0338Inherited
L domain-like0.6071Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0002482Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0002482Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0002482Direct
    50729,81837
  • 50729 - PH domain-like
  • 81837 - BEACH domain
  • 0.0004987Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.01061Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.04356Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.08448Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0002482Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0002482Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.003528Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.04235Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)