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Phenotypic Abnormality (PA): Abnormal thrombocyte morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of blood and blood-forming tissues [HP:0001871] <11>(24|35) (31|16|5)
0:   Abnormal thrombocyte morphology [HP:0001872] <4>(7|11) (7|7|4)
- 1:   Abnormal platelet function [HP:0011869] <6>(1|2) (1|0|0)
- 1:   Abnormal platelet morphology [HP:0011875] <5>(0|0) (0|0|0)
- 1:   Abnormal platelet count [HP:0011873] <2>(6|8) (6|7|4)
- 1:   Abnormal platelet volume [HP:0011876] <2>(1|1) (1|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Ras GEF0.0001187Direct
Transcription factor STAT-4 N-domain0.0005305Direct
STAT0.0005305Direct
SH2 domain0.008165Inherited
Complement control module/SCR domain0.0172Inherited
Integrin domains0.04792Inherited
L domain-like0.4819Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
Ras GEF0.00006996Direct
Transcription factor STAT-4 N-domain0.0003265Direct
STAT DNA-binding domain0.0003265Direct
STAT0.0003265Direct
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.0004518Direct
SH2 domain0.005011Inherited
Complement control module/SCR domain0.0114Inherited
Integrin domains0.03535Inherited
G proteins0.09956Inherited
Ngr ectodomain-like0.2443Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Ras GEF0.0000551Direct
Transcription factor STAT-4 N-domain0.0002689Direct
STAT0.0002689Direct
SH2 domain0.005175Inherited
Complement control module/SCR domain0.01154Inherited
Integrin domains0.0351Inherited
L domain-like0.4381Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0002689Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0002689Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0002689Direct
    50729,81837
  • 50729 - PH domain-like
  • 81837 - BEACH domain
  • 0.0005321Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.01154Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.04584Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.08812Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0002689Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0002689Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.003845Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.04429Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)