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Phenotypic Abnormality (PA): Thrombocytopenia

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of blood and blood-forming tissues [HP:0001871] <11>(22|35) (29|15|5)
+ + 2:   Abnormal thrombocyte morphology [HP:0001872] <4>(7|11) (8|7|4)
+ 1:   Abnormal platelet count [HP:0011873] <2>(6|9) (6|7|4)
0:   Thrombocytopenia [HP:0001873] <8>(4|7) (4|6|3)
- 1:   Amegakaryocytic thrombocytopenia [HP:0004859](0|0) (0|0|0)
- 1:   Autoimmune thrombocytopenia [HP:0001973](0|1) (0|0|0)
- 1:   Congenital thrombocytopenia [HP:0001905](0|0) (0|0|0)
- 1:   Heparin-induced thrombocytopenia [HP:0011874](0|0) (0|0|0)
- 1:   Intermittent thrombocytopenia [HP:0004854](0|0) (0|0|0)
- 1:   Macrothrombocytopenia [HP:0040185](1|1) (1|0|0)
- 1:   Neonatal alloimmune thrombocytopenia [HP:0004809](1|1) (1|0|0)
- 1:   Post-transfusion thrombocytopenia [HP:0004813](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Transcription factor STAT-4 N-domain0.0002359Direct
STAT0.0002359Direct
Integrin domains0.01863Inherited
L domain-like0.5382Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
STAT DNA-binding domain0.0001373Direct
STAT0.0001373Direct
Transcription factor STAT-4 N-domain0.0001373Direct
Integrin domains0.01348Inherited
DEATH domain, DD0.05103Inherited
Ngr ectodomain-like0.1664Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Transcription factor STAT-4 N-domain0.0001185Direct
STAT0.0001185Direct
Integrin domains0.0127Inherited
L domain-like0.4953Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.000104Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0001185Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0001185Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0001185Direct
    50729,81837
  • 50729 - PH domain-like
  • 81837 - BEACH domain
  • 0.0002756Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.0003523Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0001185Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0001185Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001185Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)