SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Phenotypic Abnormality (PA): Neutropenia

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   Abnormality of the immune system [HP:0002715] <3>(37|52) (39|28|15)
+ + + + + + 6:   Abnormal immune system morphology [HP:0032251] <3>(9|10) (9|6|2)
+ + + + + + 6:   Phenotypic abnormality [HP:0000118] <25>
+ + + + + 5:   Abnormal cellular immune system morphology [HP:0010987] <1>(8|9) (8|6|2)
+ + + + + 5:   Abnormality of blood and blood-forming tissues [HP:0001871] <11>(22|35) (29|15|5)
+ + + + 4:   Abnormal myeloid leukocyte morphology [HP:0010974] <3>(3|4) (4|3|2)
+ + + + 4:   Abnormal leukocyte morphology [HP:0001881] <4>(6|9) (7|5|2)
+ + + 3:   Abnormal leukocyte count [HP:0011893] <7>(3|8) (4|5|2)
+ + + 3:   Abnormal granulocyte morphology [HP:0001911] <5>(3|4) (4|3|2)
+ + 2:   Abnormality of neutrophils [HP:0001874] <3>(2|4) (3|3|2)
+ + 2:   Abnormal granulocyte count [HP:0032309] <5>(2|4) (3|3|2)
+ 1:   Abnormal neutrophil count [HP:0011991] <3>(2|4) (3|3|2)
0:   Neutropenia [HP:0001875] <4>(2|4) (3|3|2)
- 1:   Chronic neutropenia [HP:0410252] <1>(0|0) (0|0|0)
- 1:   Cyclic neutropenia [HP:0040289] <1>(0|0) (0|0|0)
- 1:   Transient neutropenia [HP:0410255] <1>(0|0) (0|0|0)
- 1:   Neutropenia in presence of anti-neutropil antibodies [HP:0001904](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Transcription factor STAT-4 N-domain0.0004112Direct
STAT0.0004112Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
STAT DNA-binding domain0.0001976Direct
STAT0.0001976Direct
Transcription factor STAT-4 N-domain0.0001976Direct
SH2 domain0.000548Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Transcription factor STAT-4 N-domain0.0002116Direct
STAT0.0002116Direct
SH2 domain0.0006431Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0002116Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0002116Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0002116Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0002116Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0002116Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)