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Phenotypic Abnormality (PA): Abnormal leukocyte morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Abnormality of the immune system [HP:0002715] <3>(37|52) (39|28|15)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormal immune system morphology [HP:0032251] <3>(9|10) (9|6|2)
+ 1:   Abnormal cellular immune system morphology [HP:0010987] <1>(8|9) (8|6|2)
+ 1:   Abnormality of blood and blood-forming tissues [HP:0001871] <11>(22|35) (29|15|5)
0:   Abnormal leukocyte morphology [HP:0001881] <4>(6|9) (7|5|2)
- 1:   Abnormal lymphocyte morphology [HP:0004332] <8>(1|2) (1|0|0)
- 1:   Abnormal leukocyte count [HP:0011893] <7>(3|8) (4|5|2)
- 1:   Leukemia [HP:0001909] <5>(0|0) (0|0|0)
- 1:   Abnormal myeloid leukocyte morphology [HP:0010974] <3>(3|4) (4|3|2)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Immunoglobulin0.0005632Direct
Transcription factor STAT-4 N-domain0.002046Inherited
STAT0.002046Inherited
DEATH domain0.009466Inherited
p53-like transcription factors0.01386Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.1183Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Pyrin domain, PYD0.0003007Direct
STAT DNA-binding domain0.001288Inherited
STAT0.001288Inherited
Transcription factor STAT-4 N-domain0.001288Inherited
Nitrogenase iron protein-like0.001288Inherited
SH2 domain0.00315Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.01405Inherited
V set domains (antibody variable domain-like)0.01908Inherited
28-residue LRR0.05027Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Immunoglobulin0.0002945Direct
Transcription factor STAT-4 N-domain0.001169Inherited
STAT0.001169Inherited
SH2 domain0.003613Inherited
DEATH domain0.006148Inherited
p53-like transcription factors0.009259Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.09467Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.001169Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.001169Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.001169Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.09467Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1586Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.001169Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.001169Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)