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Phenotypic Abnormality (PA): Abnormal bleeding

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of blood and blood-forming tissues [HP:0001871] <11>(22|35) (29|15|5)
0:   Abnormal bleeding [HP:0001892] <16>(8|15) (15|3|1)
- 1:   Internal hemorrhage [HP:0011029] <7>(7|11) (12|3|1)
- 1:   Prolonged bleeding following procedure [HP:0011890] <4>(2|2) (4|0|0)
- 1:   Subcutaneous hemorrhage [HP:0001933] <3>(1|5) (3|0|1)
- 1:   Abnormal onset of bleeding [HP:0040231] <1>(0|0) (0|0|0)
- 1:   Epistaxis [HP:0000421] <1>(3|4) (4|0|0)
- 1:   Abnormal umbilical stump bleeding [HP:0011884](0|0) (0|0|0)
- 1:   Bleeding requiring red cell transfusion [HP:0011888](0|0) (0|0|0)
- 1:   Bleeding with minor or no trauma [HP:0011889](0|0) (0|0|0)
- 1:   Cephalohematoma [HP:0012541](1|1) (1|0|0)
- 1:   Excessive bleeding after a venipuncture [HP:0030139](0|0) (0|0|0)
- 1:   Excessive bleeding from superficial cuts [HP:0030138](0|0) (0|0|0)
- 1:   Gingival bleeding [HP:0000225](1|1) (1|0|0)
- 1:   Menorrhagia [HP:0000132](1|2) (1|0|0)
- 1:   Oral cavity bleeding [HP:0030140](0|0) (0|0|0)
- 1:   Persistent bleeding after trauma [HP:0001934](0|0) (0|0|0)
- 1:   Prolonged bleeding time [HP:0003010](0|1) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.000003597Direct
Ras GEF0.0002462Direct
Fibrinogen C-terminal domain-like0.002346Inherited
Integrin domains0.07695Inherited
Snake toxin-like0.181Inherited
Trypsin-like serine proteases0.2542Inherited
L domain-like0.7729Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.000002503Direct
Ras GEF0.0001707Direct
DNA gyrase/MutL, second domain0.0001707Direct
DNA gyrase/MutL, N-terminal domain0.0001707Direct
Fibrinogen C-terminal domain-like0.001793Inherited
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)0.002015Inherited
VWC domain0.01734Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.06461Inherited
Integrin domains0.06461Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.06461Inherited
Second domain of FERM0.08739Inherited
DEATH domain, DD0.09804Inherited
Eukaryotic proteases0.1233Inherited
Ngr ectodomain-like0.3461Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.000001549Direct
Ras GEF0.0001236Direct
Fibrinogen C-terminal domain-like0.001356Inherited
Complement control module/SCR domain0.008219Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.009839Inherited
FnI-like domain0.01335Inherited
Cystine-knot cytokines0.05944Inherited
Integrin domains0.05944Inherited
EGF/Laminin0.1016Inherited
Second domain of FERM0.1506Inherited
Snake toxin-like0.1506Inherited
Trypsin-like serine proteases0.2181Inherited
L domain-like0.7375Inherited
Immunoglobulin0.7637Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0001236Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.008219Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.0114Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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