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Phenotypic Abnormality (PA): Hyperammonemia

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Phenotypic abnormality [HP:0000118] <25>
+ + + + 4:   Abnormality of metabolism/homeostasis [HP:0001939] <16>(76|83) (79|38|16)
+ + + 3:   Abnormal circulating metabolite concentration [HP:0032180] <12>(29|32) (30|14|4)
+ + 2:   Abnormal circulating nitrogen compound concentration [HP:0004364] <10>(6|6) (7|3|1)
+ 1:   Azotemia [HP:0002157] <5>(6|6) (7|3|1)
0:   Hyperammonemia [HP:0001987] <2>(5|5) (6|2|0)
- 1:   Acute hyperammonemia [HP:0008281](0|0) (0|0|0)
- 1:   Asymptomatic hyperammonemia [HP:0008162](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PreATP-grasp domain0.000001516Direct
Glutathione synthetase ATP-binding domain-like0.000005135Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.000005135Direct
Acyl-CoA dehydrogenase NM domain-like0.000005135Direct
ClpP/crotonase0.0002904Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
BC ATP-binding domain-like0.00000004298Direct
BC N-terminal domain-like0.00000004298Direct
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.0000008186Direct
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.0000008186Direct
Mitochondrial carrier0.0006572Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PreATP-grasp domain0.0000006409Direct
Acyl-CoA dehydrogenase NM domain-like0.000002232Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.000002232Direct
Glutathione synthetase ATP-binding domain-like0.000002232Direct
ClpP/crotonase0.0001472Direct
Mitochondrial carrier0.0005829Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.0000002927Direct
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.000002232Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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