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Phenotypic Abnormality (PA): Abnormality of the lymph nodes

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the cardiovascular system [HP:0001626] <5>(59|81) (72|39|29)
+ + 2:   Abnormality of the vasculature [HP:0002597] <13>(33|53) (44|26|18)
+ + 2:   Abnormality of the immune system [HP:0002715] <3>(37|52) (39|28|15)
+ 1:   Abnormality of the lymphatic system [HP:0100763] <7>(10|17) (14|6|4)
0:   Abnormality of the lymph nodes [HP:0002733] <6>(4|9) (7|5|2)
- 1:   Lymphadenopathy [HP:0002716] <5>(3|8) (6|5|2)
- 1:   Abnormality of mesenteric lymph nodes [HP:0025042] <1>(0|0) (0|0|0)
- 1:   Absence of lymph node germinal center [HP:0002849](0|0) (0|0|0)
- 1:   Increased number of lymph nodes [HP:0032536](0|0) (0|0|0)
- 1:   Lymph node hypoplasia [HP:0002732](0|0) (0|0|0)
- 1:   Lymphadenitis [HP:0002840](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
DEATH domain0.00003012Direct
TNF-like0.00008061Direct
Caspase-like0.0001451Direct
RNI-like0.0186Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
TNF-like0.00006245Direct
Caspase recruitment domain, CARD0.000396Direct
DEATH domain, DD0.007047Inherited
28-residue LRR0.03162Inherited
STAT DNA-binding domain0.06492Inherited
STAT0.06492Inherited
Pyrin domain, PYD0.06492Inherited
Transcription factor STAT-4 N-domain0.06492Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
DEATH domain0.00001382Direct
TNF-like0.00003833Direct
Caspase-like0.0000707Direct
RNI-like0.01267Inherited
Transcription factor STAT-4 N-domain0.05761Inherited
STAT0.05761Inherited
SH3-domain0.1445Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000003964Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.0002991Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.05761Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.05761Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.05761Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.05761Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.05761Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)