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Phenotypic Abnormality (PA): Autoimmunity

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the immune system [HP:0002715] <3>(38|52) (40|29|16)
+ 1:   Abnormality of immune system physiology [HP:0010978] <14>(29|37) (31|22|11)
0:   Autoimmunity [HP:0002960] <7>(4|4) (4|4|5)
- 1:   Autoimmune antibody positivity [HP:0030057] <33>(1|1) (1|0|0)
- 1:   CSF autoimmune antibody positivity [HP:0032265] <1>(0|0) (0|0|0)
- 1:   Autoimmune hemolytic anemia [HP:0001890](0|0) (0|0|0)
- 1:   Autoimmune thrombocytopenia [HP:0001973](0|0) (0|0|0)
- 1:   Hashimoto thyroiditis [HP:0000872](0|0) (0|0|0)
- 1:   Neutropenia in presence of anti-neutropil antibodies [HP:0001904](0|0) (0|0|0)
- 1:   Systemic lupus erythematosus [HP:0002725](1|1) (1|4|4)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Trypsin-like serine proteases0.00002759Direct
SH2 domain0.0004787Direct
TNF-like0.003041Inherited
Spermadhesin, CUB domain0.02476Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Eukaryotic proteases0.00001061Direct
SH2 domain0.0004601Direct
TNF-like0.002666Inherited
Spermadhesin, CUB domain0.02175Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Trypsin-like serine proteases0.00001207Direct
SH2 domain0.0002413Direct
TNF-like0.001765Inherited
Spermadhesin, CUB domain0.01712Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.00003639Direct
    57535,50494
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
  • 0.00003639Direct
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0.0001579Direct
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.000417Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,49854,57535
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.00003639Direct
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.00003639Direct
    57535,57535,50494
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
  • 0.00003639Direct
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.0001579Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.000417Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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