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Phenotypic Abnormality (PA): Colon cancer

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Phenotypic abnormality [HP:0000118] <25>
+ + + + + + 6:   Abnormality of digestive system morphology [HP:0025033] <2>(12|18) (17|6|3)
+ + + + + 5:   Neoplasm [HP:0002664] <2>(20|24) (24|8|3)
+ + + + + 5:   Abnormality of the digestive system [HP:0025031] <6>(63|72) (76|45|24)
+ + + + + 5:   Morphological abnormality of the gastrointestinal tract [HP:0012718] <8>(12|18) (17|6|3)
+ + + + 4:   Neoplasm by anatomical site [HP:0011793] <24>(18|21) (21|7|2)
+ + + + 4:   Abnormality of the gastrointestinal tract [HP:0011024] <3>(22|26) (28|11|3)
+ + + + 4:   Abnormal intestine morphology [HP:0002242] <22>(9|11) (13|3|0)
+ + + 3:   Abnormal large intestine morphology [HP:0002250] <13>(6|5) (6|2|0)
+ + + 3:   Neoplasm of the gastrointestinal tract [HP:0007378] <16>(6|5) (6|4|0)
+ + 2:   Neoplasm of the large intestine [HP:0100834] <5>(3|3) (3|2|0)
+ 1:   Neoplasm of the colon [HP:0100273] <3>(3|3) (3|2|0)
0:   Colon cancer [HP:0003003](3|3) (3|2|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
DNA repair protein MutS, domain III0.0000004493Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.000001098Direct
Ribosomal protein S5 domain 2-like0.00002147Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
DNA gyrase/MutL, second domain0.000000003671Direct
DNA gyrase/MutL, N-terminal domain0.000000003671Direct
DNA repair protein MutS, domain III0.0000003048Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
DNA repair protein MutS, domain III0.0000001863Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0000004609Direct
Ribosomal protein S5 domain 2-like0.000009762Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.000000002013Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000001863Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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