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Phenotypic Abnormality (PA): Abnormality of the coagulation cascade

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of blood and blood-forming tissues [HP:0001871] <11>(24|35) (31|16|5)
+ 1:   Abnormality of coagulation [HP:0001928] <6>(6|7) (6|3|2)
0:   Abnormality of the coagulation cascade [HP:0003256] <6>(6|6) (6|2|1)
- 1:   Abnormality of the common coagulation pathway [HP:0010990] <13>(2|3) (2|1|1)
- 1:   Abnormality of von Willebrand factor [HP:0012146] <9>(1|1) (1|0|0)
- 1:   Abnormality of the intrinsic pathway [HP:0010989] <6>(0|0) (0|0|0)
- 1:   Abnormality of prothrombin [HP:0012200] <3>(2|2) (2|0|0)
- 1:   Abnormality of the protein C anticoagulant pathway [HP:0030780] <3>(0|0) (0|0|0)
- 1:   Abnormality of the extrinsic pathway [HP:0010988] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.0000000006877Direct
Hairpin loop containing domain-like0.00002212Direct
Fibrinogen C-terminal domain-like0.002062Inherited
L domain-like0.1235Inherited
Trypsin-like serine proteases0.1637Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.0000000003643Direct
Transglutaminase core0.0005244Direct
Fibrinogen C-terminal domain-like0.001285Inherited
Ngr ectodomain-like0.02036Inherited
Eukaryotic proteases0.1372Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.0000000002618Direct
Hairpin loop containing domain-like0.000009596Direct
Fibrinogen C-terminal domain-like0.001158Inherited
L domain-like0.09873Inherited
Trypsin-like serine proteases0.1342Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.009151Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.001158Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)