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Phenotypic Abnormality (PA): Proximal muscle weakness

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the musculature [HP:0003011] <3>(64|83) (70|33|9)
+ + 2:   Abnormal muscle physiology [HP:0011804] <12>(44|59) (51|22|5)
+ 1:   Muscle weakness [HP:0001324] <22>(13|14) (15|4|0)
0:   Proximal muscle weakness [HP:0003701] <5>(4|4) (4|2|0)
- 1:   Proximal muscle weakness in lower limbs [HP:0008994] <1>(0|0) (0|0|0)
- 1:   Proximal muscle weakness in upper limbs [HP:0008997] <1>(2|2) (2|1|0)
- 1:   Gowers sign [HP:0003391](0|0) (0|0|0)
- 1:   Late-onset proximal muscle weakness [HP:0003694](1|0) (1|0|0)
- 1:   Progressive proximal muscle weakness [HP:0009073](1|1) (1|1|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Neurotransmitter-gated ion-channel transmembrane pore0.00727Inherited
Nicotinic receptor ligand binding domain-like0.00727Inherited
vWA-like0.04247Inherited
Voltage-gated potassium channels0.752Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
MIR domain0.0009798Direct
Neurotransmitter-gated ion-channel transmembrane pore0.004175Inherited
Nicotinic receptor ligand binding domain-like0.004175Inherited
Integrin A (or I) domain0.005016Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nicotinic receptor ligand binding domain-like0.004567Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.004567Inherited
vWA-like0.03068Inherited
Voltage-gated potassium channels0.7148Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.0001931Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.004567Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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