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Phenotypic Abnormality (PA): Abnormality of body weight

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Growth abnormality [HP:0001507] <6>(29|48) (34|24|15)
0:   Abnormality of body weight [HP:0004323] <4>(9|23) (13|12|3)
- 1:   Decreased body weight [HP:0004325] <6>(8|15) (9|8|2)
- 1:   Increased body weight [HP:0004324] <3>(1|7) (4|3|1)
- 1:   Abnormal waist to hip ratio [HP:0031818] <2>(0|1) (0|0|0)
- 1:   Abnormality of body mass index [HP:0045081] <2>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Glycerol-3-phosphate (1)-acyltransferase0Direct
Ribonuclease PH domain 2-like0Direct
Insulin-like0.05107Inherited
MHC antigen-recognition domain0.1032Inherited
Family A G protein-coupled receptor-like0.1419Inherited
Transcription factor STAT-4 N-domain0.2571Inherited
STAT0.2571Inherited
SET domain0.3653Inherited
vWA-like0.5876Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Ferredoxin domains from multidomain proteins0Direct
Proteasome subunits0Direct
XPF/Rad1/Mus81 nuclease0Direct
Ribonuclease PH domain 1-like0Direct
Ribonuclease PH domain 2-like0Direct
DNA gyrase/MutL, second domain0.01723Inherited
DNA gyrase/MutL, N-terminal domain0.01723Inherited
GAF domain0.04041Inherited
Insulin-like0.04041Inherited
Hypoxia-inducible factor Hif2a, C-terminal domain0.04041Inherited
Ubiquitin carboxyl-terminal hydrolase, UCH0.04041Inherited
ZZ domain0.04041Inherited
C1 set domains (antibody constant domain-like)0.04731Inherited
Rhodopsin-like0.05302Inherited
MHC antigen-recognition domain0.0873Inherited
Hect, E3 ligase catalytic domain0.1238Inherited
STAT DNA-binding domain0.2234Inherited
STAT0.2234Inherited
Transcription factor STAT-4 N-domain0.2234Inherited
Bromodomain0.3276Inherited
Integrin A (or I) domain0.3958Inherited
Phosphotyrosine-binding domain (PTB)0.4454Inherited
Histone lysine methyltransferases0.4697Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Glycerol-3-phosphate (1)-acyltransferase0Direct
Ribonuclease PH domain 2-like0Direct
GAF domain-like0.03808Inherited
Insulin-like0.03808Inherited
MHC antigen-recognition domain0.08159Inherited
Family A G protein-coupled receptor-like0.1158Inherited
Hect, E3 ligase catalytic domain0.1223Inherited
Transcription factor STAT-4 N-domain0.2208Inherited
STAT0.2208Inherited
Bromodomain0.3239Inherited
SET domain0.3239Inherited
vWA-like0.5456Inherited
Concanavalin A-like lectins/glucanases0.6764Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    52096,52096
  • 52096 - ClpP/crotonase
  • 52096 - ClpP/crotonase
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.01619Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.03808Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.03808Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.03808Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.08159Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.09866Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.2208Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.2208Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.2208Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.03808Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.2208Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.2208Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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