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Phenotypic Abnormality (PA): Decreased body weight

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Growth abnormality [HP:0001507] <6>(29|48) (34|24|15)
+ 1:   Abnormality of body weight [HP:0004323] <4>(9|23) (13|12|3)
0:   Decreased body weight [HP:0004325] <6>(8|15) (9|8|2)
- 1:   Failure to thrive [HP:0001508] <3>(2|4) (2|1|0)
- 1:   Weight loss [HP:0001824] <1>(4|8) (5|6|2)
- 1:   Decreased body mass index [HP:0045082](0|0) (0|0|0)
- 1:   Eunuchoid habitus [HP:0003782](1|1) (1|0|0)
- 1:   Slender build [HP:0001533](0|1) (0|1|0)
- 1:   Small for gestational age [HP:0001518](1|1) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Glycerol-3-phosphate (1)-acyltransferase0Direct
Ribonuclease PH domain 2-like0Direct
Insulin-like0.0292Inherited
Transcription factor STAT-4 N-domain0.03315Inherited
STAT0.03315Inherited
MHC antigen-recognition domain0.04699Inherited
vWA-like0.3081Inherited
Family A G protein-coupled receptor-like0.9948Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Ferredoxin domains from multidomain proteins0Direct
Proteasome subunits0Direct
XPF/Rad1/Mus81 nuclease0Direct
Ribonuclease PH domain 1-like0Direct
Ribonuclease PH domain 2-like0Direct
DNA gyrase/MutL, second domain0.007566Inherited
DNA gyrase/MutL, N-terminal domain0.007566Inherited
C1 set domains (antibody constant domain-like)0.01509Inherited
Insulin-like0.02156Inherited
STAT DNA-binding domain0.02495Inherited
STAT0.02495Inherited
Transcription factor STAT-4 N-domain0.02495Inherited
MHC antigen-recognition domain0.03708Inherited
Integrin A (or I) domain0.1531Inherited
Rhodopsin-like0.9872Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Glycerol-3-phosphate (1)-acyltransferase0Direct
Ribonuclease PH domain 2-like0Direct
Insulin-like0.02058Inherited
Transcription factor STAT-4 N-domain0.02372Inherited
STAT0.02372Inherited
MHC antigen-recognition domain0.03473Inherited
vWA-like0.2694Inherited
Concanavalin A-like lectins/glucanases0.7304Inherited
Family A G protein-coupled receptor-like0.9744Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.007173Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.02372Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.02372Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.02372Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.03473Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.057Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.02372Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.02372Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)