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Phenotypic Abnormality (PA): Reduced consciousness/confusion

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the nervous system [HP:0000707] <4>(147|170) (164|102|45)
+ + 2:   Abnormality of nervous system physiology [HP:0012638] <26>(104|120) (119|81|38)
+ 1:   Abnormality of higher mental function [HP:0011446] <9>(38|46) (42|25|8)
0:   Reduced consciousness/confusion [HP:0004372] <11>(11|10) (14|3|1)
- 1:   Coma [HP:0001259] <1>(4|2) (5|1|1)
- 1:   Confusion [HP:0001289] <1>(0|0) (0|0|0)
- 1:   Drowsiness [HP:0002329] <1>(0|2) (2|1|0)
- 1:   Lethargy [HP:0001254] <1>(4|6) (4|1|0)
- 1:   Decreased vigilance [HP:0032044](0|0) (0|0|0)
- 1:   Episodic hypersomnia [HP:0007200](0|0) (0|0|0)
- 1:   Excessive daytime sleepiness [HP:0002189](0|0) (0|0|0)
- 1:   Excessive daytime somnolence [HP:0001262](0|0) (0|0|0)
- 1:   Fluctuations in consciousness [HP:0007159](0|0) (0|0|0)
- 1:   Loss of consciousness [HP:0007185](0|0) (0|0|0)
- 1:   Vegetative state [HP:0031358](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
4Fe-4S ferredoxins0Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.0000433Direct
Acyl-CoA dehydrogenase NM domain-like0.0000433Direct
Mitochondrial carrier0.0002309Direct
Adenine nucleotide alpha hydrolases-like0.008385Inherited
ClpP/crotonase0.01027Inherited
NagB/RpiA/CoA transferase-like0.01627Inherited
Thiamin diphosphate-binding fold (THDP-binding)0.01627Inherited
Single hybrid motif0.01904Inherited
CoA-dependent acyltransferases0.0531Inherited
PreATP-grasp domain0.0531Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Ferredoxin domains from multidomain proteins0Direct
IF2B-like0Direct
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.0000001125Direct
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.0000001125Direct
Mitochondrial carrier0.0001288Direct
BC ATP-binding domain-like0.01151Inherited
BC N-terminal domain-like0.01151Inherited
Biotinyl/lipoyl-carrier proteins and domains0.01374Inherited
Nicotinic receptor ligand binding domain-like0.016Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.016Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
4Fe-4S ferredoxins0Direct
Acyl-CoA dehydrogenase NM domain-like0.00002012Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.00002012Direct
Mitochondrial carrier0.0001159Direct
Adenine nucleotide alpha hydrolases-like0.005407Inherited
ClpP/crotonase0.006685Inherited
NagB/RpiA/CoA transferase-like0.01098Inherited
Thiamin diphosphate-binding fold (THDP-binding)0.01098Inherited
Single hybrid motif0.01301Inherited
Nicotinic receptor ligand binding domain-like0.01506Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.01506Inherited
PreATP-grasp domain0.03975Inherited
CoA-dependent acyltransferases0.03975Inherited
Glutathione synthetase ATP-binding domain-like0.06027Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.00002012Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.01506Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.02328Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.01919Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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