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Phenotypic Abnormality (PA): Lipid accumulation in hepatocytes

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Phenotypic abnormality [HP:0000118] <25>
+ + + + + 5:   Abnormality of the digestive system [HP:0025031] <6>(67|77) (77|47|25)
+ + + + 4:   Abnormality of the abdominal organs [HP:0002012] <6>(27|27) (30|14|4)
+ + + 3:   Abnormality of the liver [HP:0001392] <4>(17|12) (17|7|0)
+ + 2:   Abnormal liver morphology [HP:0410042] <25>(13|9) (13|4|0)
+ 1:   Storage in hepatocytes [HP:0031137] <1>(6|4) (6|2|0)
0:   Lipid accumulation in hepatocytes [HP:0006561] <2>(6|4) (6|2|0)
- 1:   Hepatic steatosis [HP:0001397] <4>(6|4) (6|2|0)
- 1:   Increased hepatocellular lipid droplets [HP:0006565](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Acyl-CoA dehydrogenase C-terminal domain-like1Inherited
Nucleotidylyl transferase1Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like1Inherited
Acyl-CoA dehydrogenase NM domain-like1Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases1Inherited
Adenine nucleotide alpha hydrolases-like1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases1Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain1Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain1Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases1Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like1Inherited
Adenine nucleotide alpha hydrolases-like1Inherited
Nucleotidylyl transferase1Inherited
Acyl-CoA dehydrogenase NM domain-like1Inherited
Acyl-CoA dehydrogenase C-terminal domain-like1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 1Inherited
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 1Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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