SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Phenotypic Abnormality (PA): Aplasia/Hypoplasia of the cerebrum

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Phenotypic abnormality [HP:0000118] <25>
+ + + + 4:   Abnormality of the nervous system [HP:0000707] <4>(147|170) (164|102|45)
+ + + 3:   Abnormality of brain morphology [HP:0012443] <13>(44|63) (54|31|14)
+ + + 3:   Abnormality of nervous system morphology [HP:0012639] <5>(70|97) (81|48|16)
+ + 2:   Abnormality of forebrain morphology [HP:0100547] <6>(26|28) (29|15|4)
+ + 2:   Morphological abnormality of the central nervous system [HP:0002011] <17>(61|85) (71|41|16)
+ 1:   Aplasia/Hypoplasia involving the central nervous system [HP:0002977] <13>(18|22) (22|10|2)
+ 1:   Abnormality of the cerebrum [HP:0002060] <16>(25|27) (28|15|4)
0:   Aplasia/Hypoplasia of the cerebrum [HP:0007364] <5>(11|15) (12|5|1)
- 1:   Anencephaly [HP:0002323] <2>(0|1) (0|0|0)
- 1:   Aplasia/Hypoplasia of the corpus callosum [HP:0007370] <2>(3|4) (3|1|0)
- 1:   Cerebral hypoplasia [HP:0006872] <2>(0|0) (0|0|0)
- 1:   Microcephaly [HP:0000252] <2>(7|10) (9|3|1)
- 1:   Aprosencephaly [HP:0007268](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Pseudouridine synthase0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
Restriction endonuclease-like0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Acyl-CoA N-acyltransferases (Nat)0Direct
ARID-like0.004144Inherited
Nucleotidylyl transferase0.06881Inherited
Ribonuclease H-like0.107Inherited
NagB/RpiA/CoA transferase-like0.3898Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Ferredoxin domains from multidomain proteins0Direct
IF2B-like0Direct
XPF/Rad1/Mus81 nuclease0Direct
Ypt/Rab-GAP domain of gyp1p0Direct
N-acetyl transferase, NAT0Direct
Clathrin adaptor core protein0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
SWIRM domain0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
ARID domain0.002037Inherited
Bromodomain0.002264Inherited
PHD domain0.04475Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.05624Inherited
T-box0.2639Inherited
Homeodomain0.3045Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Ypt/Rab-GAP domain of gyp1p0Direct
Pseudouridine synthase0Direct
Restriction endonuclease-like0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Acyl-CoA N-acyltransferases (Nat)0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
ARID-like0.00252Inherited
Bromodomain0.003222Inherited
Nucleotidylyl transferase0.05264Inherited
Ribonuclease H-like0.08483Inherited
NagB/RpiA/CoA transferase-like0.3479Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0Direct
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)