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Phenotypic Abnormality (PA): Peripheral neuropathy

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the nervous system [HP:0000707] <4>(147|170) (164|102|45)
+ + 2:   Abnormality of nervous system morphology [HP:0012639] <5>(70|97) (81|48|16)
+ 1:   Abnormal peripheral nervous system morphology [HP:0000759] <14>(14|17) (17|6|0)
0:   Peripheral neuropathy [HP:0009830] <17>(7|11) (8|4|0)
- 1:   Sensory impairment [HP:0003474] <7>(1|4) (1|0|0)
- 1:   Sensory neuropathy [HP:0000763] <6>(4|5) (5|3|0)
- 1:   Demyelinating peripheral neuropathy [HP:0007108] <3>(1|0) (1|0|0)
- 1:   Entrapment neuropathy [HP:0012181] <3>(0|0) (0|0|0)
- 1:   Peripheral axonal neuropathy [HP:0003477] <3>(0|0) (0|0|0)
- 1:   Motor polyneuropathy [HP:0007178] <1>(0|0) (0|0|0)
- 1:   Acute episodes of neuropathic symptoms [HP:0003489](0|0) (0|0|0)
- 1:   Chronic sensorineural polyneuropathy [HP:0001301](0|0) (0|0|0)
- 1:   Congenital peripheral neuropathy [HP:0006903](0|0) (0|0|0)
- 1:   Episodic peripheral neuropathy [HP:0006949](0|0) (0|0|0)
- 1:   Mixed demyelinating and axonal polyneuropathy [HP:0007327](0|0) (0|0|0)
- 1:   Mononeuropathy [HP:0009831](0|0) (0|0|0)
- 1:   Multiple mononeuropathy [HP:0032018](0|0) (0|0|0)
- 1:   Polyneuropathy [HP:0001271](0|0) (0|0|0)
- 1:   Progressive peripheral neuropathy [HP:0007133](0|0) (0|0|0)
- 1:   Sensorimotor neuropathy [HP:0007141](0|0) (0|0|0)
- 1:   Sensorimotor polyneuropathy affecting arms more than legs [HP:0006865](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
MHC antigen-recognition domain0.0002361Direct
S15/NS1 RNA-binding domain0.003931Inherited
Voltage-gated potassium channels0.01553Inherited
Glycosyl hydrolase domain0.0228Inherited
Ribosomal protein S5 domain 2-like0.07353Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1506Inherited
Ribonuclease H-like0.3069Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
alpha-Amylases, C-terminal beta-sheet domain0Direct
MHC antigen-recognition domain0.000103Direct
C1 set domains (antibody constant domain-like)0.000121Direct
DNA gyrase/MutL, second domain0.0003752Direct
DNA gyrase/MutL, N-terminal domain0.0003752Direct
a tRNA synthase domain0.002187Inherited
Amylase, catalytic domain0.007482Inherited
Extended AAA-ATPase domain0.111Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.1457Inherited
Myotubularin-like phosphatases0.3307Inherited
Transducin (alpha subunit), insertion domain0.3307Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
MHC antigen-recognition domain0.0001186Direct
S15/NS1 RNA-binding domain0.002379Inherited
Voltage-gated potassium channels0.01046Inherited
Glycosyl hydrolase domain0.01583Inherited
Ribosomal protein S5 domain 2-like0.0566Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1236Inherited
Ribonuclease H-like0.2682Inherited
Transducin (alpha subunit), insertion domain0.3484Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.0001186Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0004141Direct
    51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0.01583Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3484Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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