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Phenotypic Abnormality (PA): Abnormality of the curvature of the vertebral column

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Phenotypic abnormality [HP:0000118] <25>
+ + + + 4:   Abnormality of the skeletal system [HP:0000924] <7>(89|98) (94|51|33)
+ + + 3:   Abnormality of skeletal morphology [HP:0011842] <18>(87|89) (90|49|32)
+ + 2:   Abnormal axial skeleton morphology [HP:0009121] <6>(48|61) (53|28|26)
+ 1:   Abnormality of the vertebral column [HP:0000925] <20>(21|27) (25|11|10)
0:   Abnormality of the curvature of the vertebral column [HP:0010674] <6>(12|15) (13|7|4)
- 1:   Scoliosis [HP:0002650] <5>(7|11) (8|7|4)
- 1:   Kyphosis [HP:0002808] <3>(3|3) (3|1|2)
- 1:   Abnormal cervical curvature [HP:0005905] <1>(2|2) (2|1|0)
- 1:   Hyperlordosis [HP:0003307] <1>(1|1) (1|0|0)
- 1:   Abnormally straight spine [HP:0100795](0|0) (0|0|0)
- 1:   Camptocormia [HP:0100595](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
C-terminal, gelsolin-like domain of Sec23/240Direct
Restriction endonuclease-like0Direct
Helical domain of Sec23/240Direct
RuvA domain 2-like0Direct
Zn-finger domain of Sec23/240Direct
Nucleotide-diphospho-sugar transferases0.0002194Direct
Notch domain0.01663Inherited
FKBP-like0.01663Inherited
GST C-terminal domain-like0.1287Inherited
MIR domain0.1287Inherited
Nicotinic receptor ligand binding domain-like0.2098Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.2098Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Myotubularin-like phosphatases0Direct
beta-sandwich domain of Sec23/240Direct
XPF/Rad1/Mus81 nuclease0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Exostosin0Direct
Trunk domain of Sec23/240Direct
Zn-finger domain of Sec23/240Direct
Helical domain of Sec23/240Direct
Regulator of chromosome condensation RCC10.0008638Direct
beta-glycanases0.01122Inherited
FKBP immunophilin/proline isomerase0.01122Inherited
Notch domain0.01122Inherited
MIR domain0.1033Inherited
Nicotinic receptor ligand binding domain-like0.1754Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.1754Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
C-terminal, gelsolin-like domain of Sec23/240Direct
Helical domain of Sec23/240Direct
RuvA domain 2-like0Direct
Restriction endonuclease-like0Direct
Zn-finger domain of Sec23/240Direct
Nucleotide-diphospho-sugar transferases0.0001097Direct
beta-sandwich domain of Sec23/240.001136Inherited
FKBP-like0.01126Inherited
Notch domain0.01126Inherited
MIR domain0.104Inherited
GST C-terminal domain-like0.104Inherited
Nicotinic receptor ligand binding domain-like0.1769Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.1769Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.1769Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4563Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.518Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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