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Phenotypic Abnormality (PA): Abnormal cellular immune system morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the immune system [HP:0002715] <3>(38|52) (40|29|16)
+ 1:   Abnormal immune system morphology [HP:0032251] <3>(11|11) (11|6|2)
0:   Abnormal cellular immune system morphology [HP:0010987] <1>(10|10) (10|6|2)
- 1:   Abnormal leukocyte morphology [HP:0001881] <4>(8|9) (9|5|2)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SH2 domain0.000000592Direct
DEATH domain0.000007445Direct
TNF receptor-like0.0005883Direct
Transcription factor STAT-4 N-domain0.002021Inherited
STAT0.002021Inherited
RNI-like0.004376Inherited
p53-like transcription factors0.01451Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.03241Inherited
FYVE/PHD zinc finger0.3042Inherited
Immunoglobulin0.6207Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
SH2 domain0.0000003834Direct
Pyrin domain, PYD0.0003022Direct
Tandem AAA-ATPase domain0.0004585Direct
Nitrogenase iron protein-like0.001292Inherited
Transcription factor STAT-4 N-domain0.001292Inherited
STAT DNA-binding domain0.001292Inherited
STAT0.001292Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.01401Inherited
28-residue LRR0.01881Inherited
V set domains (antibody variable domain-like)0.01909Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SH2 domain0.0000002337Direct
DEATH domain0.000003093Direct
TNF receptor-like0.0003004Direct
Transcription factor STAT-4 N-domain0.001133Inherited
STAT0.001133Inherited
RNI-like0.002633Inherited
p53-like transcription factors0.009612Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.02289Inherited
FYVE/PHD zinc finger0.2642Inherited
Immunoglobulin0.5791Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0002988Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.001133Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.001133Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.001133Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.00144Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.005888Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.001133Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.001133Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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