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Phenotypic Abnormality (PA): Abnormality of the common coagulation pathway

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of blood and blood-forming tissues [HP:0001871] <11>(24|35) (31|16|5)
+ + 2:   Abnormality of coagulation [HP:0001928] <6>(6|7) (6|3|2)
+ 1:   Abnormality of the coagulation cascade [HP:0003256] <6>(6|6) (6|2|1)
0:   Abnormality of the common coagulation pathway [HP:0010990] <13>(2|3) (2|1|1)
- 1:   Abnormality of circulating fibrinogen [HP:0011898] <3>(2|2) (2|0|0)
- 1:   Abnormal coagulation factor V activity [HP:0031899] <2>(0|0) (0|0|0)
- 1:   Reduced factor XIII activity [HP:0008357] <2>(0|0) (0|0|0)
- 1:   Reduced factor X activity [HP:0008321] <1>(0|0) (0|0|0)
- 1:   Decreased level of heparin co-factor II [HP:0040226](0|0) (0|0|0)
- 1:   Decreased level of histidine-rich glycoprotein [HP:0040227](0|0) (0|0|0)
- 1:   Decreased level of plasminogen [HP:0040228](0|0) (0|0|0)
- 1:   Decreased level of thrombomodulin [HP:0040229](0|0) (0|0|0)
- 1:   Decreased level of tissue plasminogen activator [HP:0040230](0|0) (0|0|0)
- 1:   Increased plasma vitamin K epoxide after vitamin K supplementation [HP:0040239](0|0) (0|0|0)
- 1:   Prolonged Russell's viper venom time [HP:0040244](0|0) (0|0|0)
- 1:   Reduced alpha-2-antiplasmin activity [HP:0040245](0|0) (0|0|0)
- 1:   Reduced antithrombin antigen [HP:0040246](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
Fibrinogen C-terminal domain-like0.0001468Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
Transglutaminase core0.00003136Direct
Fibrinogen C-terminal domain-like0.0000856Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
Fibrinogen C-terminal domain-like0.00006898Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.0007316Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.00006898Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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