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Phenotypic Abnormality (PA): Abnormality of the gastrointestinal tract

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of the digestive system [HP:0025031] <6>(63|72) (76|45|24)
0:   Abnormality of the gastrointestinal tract [HP:0011024] <3>(22|26) (28|11|3)
- 1:   Neoplasm of the gastrointestinal tract [HP:0007378] <16>(6|5) (6|4|0)
- 1:   Functional abnormality of the gastrointestinal tract [HP:0012719] <11>(9|11) (14|2|0)
- 1:   Morphological abnormality of the gastrointestinal tract [HP:0012718] <8>(12|18) (17|6|3)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Zn-finger domain of Sec23/240Direct
SAND domain-like0Direct
CalX-like0.02123Inherited
Immunoglobulin0.04477Inherited
DNA repair protein MutS, domain III0.04762Inherited
Integrin domains0.08186Inherited
BRCT domain0.1182Inherited
SH3-domain0.1515Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1547Inherited
RNI-like0.2098Inherited
Ribosomal protein S5 domain 2-like0.2103Inherited
Actin-like ATPase domain0.2103Inherited
Protein kinase-like (PK-like)0.2529Inherited
Snake toxin-like0.2736Inherited
DEATH domain0.5157Inherited
Ran binding protein zinc finger-like0.5256Inherited
SET domain0.6094Inherited
L domain-like0.9108Inherited
alpha/beta-Hydrolases0.9276Inherited
Intermediate filament protein, coiled coil region0.9456Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
DNA polymerase I0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
P4 origin-binding domain-like0Direct
Fibrinogen coiled-coil and central regions0Direct
Zn-finger domain of Sec23/240Direct
DnaQ-like 3'-5' exonuclease0.006165Inherited
C1 set domains (antibody constant domain-like)0.01258Inherited
DNA gyrase/MutL, second domain0.01542Inherited
DNA gyrase/MutL, N-terminal domain0.01542Inherited
CalX-beta domain0.01542Inherited
Transforming growth factor (TGF)-beta0.02208Inherited
DNA repair protein MutS, domain III0.03709Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.03709Inherited
Actin/HSP700.0652Inherited
Integrin domains0.0652Inherited
RecA protein-like (ATPase-domain)0.0652Inherited
SNARE fusion complex0.09589Inherited
KRAB domain (Kruppel-associated box)0.1697Inherited
Laminin-type module0.1717Inherited
SH3-domain0.1729Inherited
Extended AAA-ATPase domain0.1811Inherited
28-residue LRR0.3892Inherited
Ran binding protein zinc finger-like0.4873Inherited
Histone lysine methyltransferases0.6395Inherited
Ngr ectodomain-like0.8361Inherited
Intermediate filament protein, coiled coil region0.9383Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SAND domain-like0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Fibrinogen coiled-coil and central regions0Direct
Zn-finger domain of Sec23/240Direct
beta-sandwich domain of Sec23/240.0007952Direct
DNA/RNA polymerases0.00216Inherited
CalX-like0.01465Inherited
Immunoglobulin0.03291Inherited
DNA repair protein MutS, domain III0.03526Inherited
Integrin domains0.06357Inherited
SNARE fusion complex0.09205Inherited
BRCT domain0.09453Inherited
SH3-domain0.1244Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1273Inherited
KRAB domain (Kruppel-associated box)0.164Inherited
RNI-like0.1769Inherited
Ribosomal protein S5 domain 2-like0.1775Inherited
Actin-like ATPase domain0.1775Inherited
Protein kinase-like (PK-like)0.2168Inherited
4-helical cytokines0.2367Inherited
Snake toxin-like0.2367Inherited
RING/U-box0.4541Inherited
DEATH domain0.4724Inherited
Ran binding protein zinc finger-like0.4824Inherited
SET domain0.5687Inherited
L domain-like0.8825Inherited
alpha/beta-Hydrolases0.9004Inherited
Intermediate filament protein, coiled coil region0.9196Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01291Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.01465Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.03526Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03526Inherited
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.03526Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.134Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.2068Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1666Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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