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Phenotypic Abnormality (PA): Abnormality of skin adnexa morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of the integument [HP:0001574] <4>(46|69) (58|36|15)
0:   Abnormality of skin adnexa morphology [HP:0011138] <5>(15|20) (16|6|2)
- 1:   Abnormality of the nail [HP:0001597] <25>(4|4) (4|3|1)
- 1:   Abnormal hair morphology [HP:0001595] <12>(13|19) (14|4|1)
- 1:   Skin appendage neoplasm [HP:0012842] <8>(0|0) (0|0|0)
- 1:   Abnormal sebaceous gland morphology [HP:0032226] <2>(0|0) (0|0|0)
- 1:   Abnormal sweat gland morphology [HP:0000971] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Smc hinge domain0Direct
Notch domain0Direct
CCCH zinc finger0Direct
Plakin repeat0Direct
SET domain0.004033Inherited
BRK domain-like0.02776Inherited
Histone-fold0.03128Inherited
ARID-like0.03128Inherited
Bromodomain0.04007Inherited
Intermediate filament protein, coiled coil region0.04885Inherited
BRCT domain0.05252Inherited
GroEL equatorial domain-like0.1797Inherited
MHC antigen-recognition domain0.2303Inherited
EGF/Laminin0.5808Inherited
RING/U-box0.7358Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Plakin repeat0Direct
CCCH zinc finger0Direct
Smc hinge domain0Direct
Notch domain0Direct
Histone lysine methyltransferases0.0003584Direct
BRK domain-like0.01963Inherited
ARID domain0.02235Inherited
Bromodomain0.02739Inherited
Intermediate filament protein, coiled coil region0.03306Inherited
Hect, E3 ligase catalytic domain0.03357Inherited
TBP-associated factors, TAFs0.05472Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.1017Inherited
MHC antigen-recognition domain0.19Inherited
Laminin-type module0.2624Inherited
Spermadhesin, CUB domain0.2958Inherited
Actin/HSP700.3578Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.3578Inherited
Extended AAA-ATPase domain0.4642Inherited
C1 set domains (antibody constant domain-like)0.5192Inherited
ABC transporter ATPase domain-like0.9436Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Smc hinge domain0Direct
Plakin repeat0Direct
CCCH zinc finger0Direct
Notch domain0Direct
SET domain0.002446Inherited
BRK domain-like0.01948Inherited
Histone-fold0.02226Inherited
ARID-like0.02226Inherited
Bromodomain0.02909Inherited
Hect, E3 ligase catalytic domain0.035Inherited
Intermediate filament protein, coiled coil region0.03629Inherited
BRCT domain0.03923Inherited
GroEL equatorial domain-like0.1493Inherited
MHC antigen-recognition domain0.1957Inherited
EGF/Laminin0.5387Inherited
RING/U-box0.6989Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.09287Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1451Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.1957Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.1957Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4201Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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