SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Phenotypic Abnormality (PA): Abnormality of joint mobility

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the skeletal system [HP:0000924] <7>(89|98) (94|51|33)
+ 1:   Abnormality of skeletal physiology [HP:0011843] <8>(16|23) (18|15|15)
0:   Abnormality of joint mobility [HP:0011729] <6>(15|21) (17|15|15)
- 1:   Limitation of joint mobility [HP:0001376] <13>(2|2) (2|7|12)
- 1:   Flexion contracture [HP:0001371] <9>(7|10) (7|7|1)
- 1:   Joint hypermobility [HP:0001382] <8>(5|9) (5|3|1)
- 1:   Synostosis of joints [HP:0100240] <7>(3|1) (4|0|0)
- 1:   Joint laxity [HP:0001388] <2>(0|1) (1|1|0)
- 1:   Abnormality of hand joint mobility [HP:0006256] <1>(1|1) (1|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
TB module/8-cys domain0Direct
Ribonuclease PH domain 2-like0Direct
Tropomyosin0.01922Inherited
C-terminal, gelsolin-like domain of Sec23/240.02032Inherited
Helical domain of Sec23/240.02032Inherited
ARID-like0.02177Inherited
Troponin coil-coiled subunits0.05359Inherited
Calponin-homology domain, CH-domain0.1081Inherited
vWA-like0.1197Inherited
MIR domain0.1493Inherited
SET domain0.2208Inherited
Bromodomain0.2561Inherited
Spectrin repeat0.3478Inherited
Histone-fold0.5492Inherited
Cystine-knot cytokines0.8546Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
Ribonuclease PH domain 1-like0Direct
Ribonuclease PH domain 2-like0Direct
TB module/8-cys domain0Direct
DNA gyrase/MutL, second domain0.004486Inherited
DNA gyrase/MutL, N-terminal domain0.004486Inherited
VWC domain0.005509Inherited
Tropomyosin0.0139Inherited
beta-sandwich domain of Sec23/240.01457Inherited
C-terminal, gelsolin-like domain of Sec23/240.01457Inherited
Trunk domain of Sec23/240.01457Inherited
Helical domain of Sec23/240.01457Inherited
Ras-binding domain, RBD0.01578Inherited
ARID domain0.01578Inherited
PHD domain0.06961Inherited
Calponin-homology domain, CH-domain0.09067Inherited
MIR domain0.1262Inherited
Integrin A (or I) domain0.1525Inherited
Bromodomain0.2138Inherited
Spectrin repeat0.3Inherited
Rhodopsin-like1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Ribonuclease PH domain 2-like0Direct
TB module/8-cys domain0Direct
Tropomyosin0.01314Inherited
C-terminal, gelsolin-like domain of Sec23/240.01396Inherited
Helical domain of Sec23/240.01396Inherited
ARID-like0.01504Inherited
Troponin coil-coiled subunits0.04014Inherited
Calponin-homology domain, CH-domain0.0858Inherited
vWA-like0.09588Inherited
MIR domain0.1225Inherited
SET domain0.1868Inherited
Bromodomain0.2199Inherited
Spectrin repeat0.3073Inherited
HLH, helix-loop-helix DNA-binding domain0.4139Inherited
Histone-fold0.5064Inherited
Cystine-knot cytokines0.8227Inherited
Family A G protein-coupled receptor-like0.9912Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57581,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.004157Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.004263Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.008471Inherited
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.01396Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.03285Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.04014Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.06882Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.08432Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1483Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.5064Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57581,57184
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57581,57184,57581
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.005223Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.03225Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.04366Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.04869Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)