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Phenotypic Abnormality (PA): Abnormal leukocyte count

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Abnormality of the immune system [HP:0002715] <3>(37|52) (39|28|15)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormal immune system morphology [HP:0032251] <3>(9|10) (9|6|2)
+ + 2:   Abnormality of blood and blood-forming tissues [HP:0001871] <11>(22|35) (29|15|5)
+ + 2:   Abnormal cellular immune system morphology [HP:0010987] <1>(8|9) (8|6|2)
+ 1:   Abnormal leukocyte morphology [HP:0001881] <4>(6|9) (7|5|2)
0:   Abnormal leukocyte count [HP:0011893] <7>(3|8) (4|5|2)
- 1:   Abnormal granulocyte count [HP:0032309] <5>(2|4) (3|3|2)
- 1:   Abnormal lymphocyte count [HP:0040088] <4>(0|1) (0|0|0)
- 1:   Abnormal monocyte count [HP:0012310] <2>(0|0) (0|0|0)
- 1:   Leukocytosis [HP:0001974] <2>(0|2) (0|1|0)
- 1:   Leukopenia [HP:0001882] <1>(3|5) (3|3|2)
- 1:   Abnormal dendritic cell count [HP:0020178](0|0) (0|0|0)
- 1:   Increased peripheral blast count [HP:0032372](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Transcription factor STAT-4 N-domain0.0003651Direct
STAT0.0003651Direct
p53-like transcription factors0.2745Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Pyrin domain, PYD0.00004463Direct
STAT DNA-binding domain0.0002135Direct
STAT0.0002135Direct
Transcription factor STAT-4 N-domain0.0002135Direct
Nitrogenase iron protein-like0.0002135Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.00387Inherited
28-residue LRR0.004112Inherited
SH2 domain0.1235Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Transcription factor STAT-4 N-domain0.0001871Direct
STAT0.0001871Direct
SH2 domain0.1238Inherited
p53-like transcription factors0.2374Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001777Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0001871Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0001871Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0001871Direct
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001521Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0001871Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0001871Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)