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Phenotypic Abnormality (PA): Abnormal reproductive system morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the genitourinary system [HP:0000119] <5>(73|72) (80|28|9)
+ 1:   Abnormality of the genital system [HP:0000078] <3>(35|34) (37|10|3)
0:   Abnormal reproductive system morphology [HP:0012243] <10>(28|27) (29|4|1)
- 1:   Abnormal internal genitalia [HP:0000812] <9>(15|17) (16|2|0)
- 1:   Abnormal external genitalia [HP:0000811] <7>(15|11) (16|1|1)
- 1:   Abnormality of the female genitalia [HP:0010460] <2>(16|18) (18|2|0)
- 1:   Abnormality of the male genitalia [HP:0010461] <2>(14|11) (16|1|1)
- 1:   Abnormal germ cell morphology [HP:0012862] <1>(1|0) (1|0|0)
- 1:   Abnormal meiosis [HP:0031515] <1>(0|0) (0|0|0)
- 1:   Abnormal sex determination [HP:0012244] <1>(0|0) (0|0|0)
- 1:   Genital tract atresia [HP:0001827] <1>(0|0) (0|0|0)
- 1:   Anteriorly displaced genitalia [HP:0003252](0|0) (0|0|0)
- 1:   Genital ulcers [HP:0003249](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Lamin A/C globular tail domain0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
DNA repair protein MutS, domain III0Direct
Smc hinge domain0Direct
Fibrinogen coiled-coil and central regions0Direct
Zn-finger domain of Sec23/240Direct
SET domain0.0002778Direct
Bromodomain0.001637Inherited
RING/U-box0.007153Inherited
CalX-like0.01365Inherited
BRCT domain0.01867Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.03593Inherited
NagB/RpiA/CoA transferase-like0.07828Inherited
GroEL equatorial domain-like0.08567Inherited
Fibrinogen C-terminal domain-like0.1061Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.201Inherited
FYVE/PHD zinc finger0.2663Inherited
Nuclear receptor ligand-binding domain0.4355Inherited
Ribonuclease H-like0.467Inherited
Family A G protein-coupled receptor-like0.526Inherited
Ribosomal protein S5 domain 2-like0.5271Inherited
Clavaminate synthase-like0.5755Inherited
Trypsin-like serine proteases0.6506Inherited
ARID-like0.6632Inherited
WD40 repeat-like0.7596Inherited
Cytochrome P4500.8165Inherited
"Winged helix" DNA-binding domain0.8202Inherited
DEATH domain0.9061Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
DNA repair protein MutS, domain III0Direct
Lamin A/C globular tail domain0Direct
Smc hinge domain0Direct
DIX domain0Direct
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
Fibrinogen coiled-coil and central regions0Direct
IF2B-like0Direct
Histone lysine methyltransferases0.0007128Direct
Bromodomain0.001037Inherited
RING finger domain, C3HC40.001834Inherited
RecA protein-like (ATPase-domain)0.005807Inherited
CalX-beta domain0.009577Inherited
DNA gyrase/MutL, second domain0.009577Inherited
DNA gyrase/MutL, N-terminal domain0.009577Inherited
Fibrinogen C-terminal domain-like0.08858Inherited
Extracellular domain of cell surface receptors0.1271Inherited
ABC transporter ATPase domain-like0.2589Inherited
PHD domain0.2635Inherited
HMG-box0.3825Inherited
Nuclear receptor ligand-binding domain0.412Inherited
Nuclear receptor0.4428Inherited
Rhodopsin-like0.4564Inherited
Extended AAA-ATPase domain0.5124Inherited
Ngr ectodomain-like0.5709Inherited
Eukaryotic proteases0.5815Inherited
ARID domain0.641Inherited


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Smc hinge domain0Direct
Fibrinogen coiled-coil and central regions0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
DNA repair protein MutS, domain III0Direct
Lamin A/C globular tail domain0Direct
Zn-finger domain of Sec23/240Direct
SET domain0.0001359Direct
Bromodomain0.0009002Direct
RING/U-box0.004486Inherited
CalX-like0.009017Inherited
BRCT domain0.01259Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0257Inherited
NagB/RpiA/CoA transferase-like0.06014Inherited
GroEL equatorial domain-like0.06642Inherited
Fibrinogen C-terminal domain-like0.08369Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.1682Inherited
FYVE/PHD zinc finger0.2283Inherited
HMG-box0.3622Inherited
Nuclear receptor ligand-binding domain0.3915Inherited
Ribonuclease H-like0.4232Inherited
Family A G protein-coupled receptor-like0.4817Inherited
Ribosomal protein S5 domain 2-like0.4828Inherited
Clavaminate synthase-like0.5327Inherited
Trypsin-like serine proteases0.61Inherited
ARID-like0.6226Inherited
WD40 repeat-like0.7226Inherited
Cytochrome P4500.7822Inherited
"Winged helix" DNA-binding domain0.7861Inherited
DEATH domain0.8774Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.009017Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.01197Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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