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Phenotypic Abnormality (PA): Impairment in personality functioning

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the nervous system [HP:0000707] <4>(147|170) (164|102|45)
+ + 2:   Abnormality of nervous system physiology [HP:0012638] <26>(104|120) (119|81|38)
+ 1:   Behavioral abnormality [HP:0000708] <38>(15|25) (20|16|6)
0:   Impairment in personality functioning [HP:0031466] <12>(6|8) (7|3|0)
- 1:   Abnormal fear/anxiety-related behavior [HP:0100852] <4>(2|4) (2|1|0)
- 1:   Inappropriate behavior [HP:0000719] <4>(0|0) (0|0|0)
- 1:   Disinhibition [HP:0000734] <2>(0|0) (1|1|0)
- 1:   Personality disorder [HP:0012075] <2>(0|0) (0|0|0)
- 1:   Anhedonia [HP:0012154](0|0) (0|0|0)
- 1:   Bipolar affective disorder [HP:0007302](0|0) (0|0|0)
- 1:   Depressivity [HP:0000716](2|4) (2|1|0)
- 1:   Emotional lability [HP:0000712](2|2) (2|0|0)
- 1:   Hostility [HP:0031473](0|0) (0|0|0)
- 1:   Low self esteem [HP:0031469](2|2) (2|1|0)
- 1:   Negative affectivity [HP:0031467](0|0) (0|0|0)
- 1:   Separation insecurity [HP:0031468](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Cap-Gly domain0.003009Inherited
Calcium-dependent phosphotriesterase0.003009Inherited
Bromodomain0.008645Inherited
NagB/RpiA/CoA transferase-like0.07676Inherited
Nicotinic receptor ligand binding domain-like0.116Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.116Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
IF2B-like0Direct
Serum paraoxonase/arylesterase 1, PON10Direct
DNA gyrase/MutL, second domain0.0002615Direct
DNA gyrase/MutL, N-terminal domain0.0002615Direct
Cap-Gly domain0.001666Inherited
Bromodomain0.004594Inherited
Nicotinic receptor ligand binding domain-like0.08346Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.08346Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Cap-Gly domain0.001777Inherited
Calcium-dependent phosphotriesterase0.001777Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.004371Inherited
Bromodomain0.005581Inherited
NagB/RpiA/CoA transferase-like0.05933Inherited
Nicotinic receptor ligand binding domain-like0.09258Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.09258Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0002774Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.02839Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.09258Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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