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Phenotypic Abnormality (PA): Abnormal ear morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of the ear [HP:0000598] <2>(18|32) (22|13|10)
0:   Abnormal ear morphology [HP:0031703] <5>(15|26) (18|11|10)
- 1:   Abnormality of the outer ear [HP:0000356] <14>(6|7) (7|3|1)
- 1:   Abnormality of the middle ear [HP:0000370] <10>(1|5) (1|1|5)
- 1:   Abnormality of the inner ear [HP:0000359] <5>(6|9) (8|4|3)
- 1:   Aplasia/Hypoplasia of the ear [HP:0008771] <3>(0|0) (0|0|0)
- 1:   Neoplasm of the ear [HP:0012780] <3>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Smc hinge domain0Direct
ADC-like0Direct
4Fe-4S ferredoxins0Direct
JAB1/MPN domain0Direct
RuvA domain 2-like0Direct
L27 domain0Direct
SET domain0.03063Inherited
Integrin domains0.06674Inherited
Acyl-CoA N-acyltransferases (Nat)0.174Inherited
Transcription factor STAT-4 N-domain0.2813Inherited
STAT0.2813Inherited
Bromodomain0.4938Inherited
MIR domain0.7057Inherited
GroEL equatorial domain-like0.7595Inherited
Family A G protein-coupled receptor-like0.9322Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Ferredoxin domains from multidomain proteins0Direct
L27 domain0Direct
RhoGDI-like0Direct
Smc hinge domain0Direct
XPF/Rad1/Mus81 nuclease0Direct
Histone deacetylase, HDAC0Direct
JAB1/MPN domain0Direct
Lipoxigenase N-terminal domain0Direct
Enabled/VASP homology 1 domain (EVH1 domain)0Direct
VWC domain0.005902Inherited
PHD domain0.008136Inherited
ARID domain0.01307Inherited
Histone lysine methyltransferases0.028Inherited
Integrin domains0.05059Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.0592Inherited
I set domains0.06293Inherited
G proteins0.1264Inherited
C1 set domains (antibody constant domain-like)0.1903Inherited
STAT DNA-binding domain0.2435Inherited
STAT0.2435Inherited
Transcription factor STAT-4 N-domain0.2435Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.2695Inherited
Bromodomain0.4746Inherited
MIR domain0.6899Inherited
Pleckstrin-homology domain (PH domain)0.7261Inherited
Rhodopsin-like0.9317Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
JAB1/MPN domain0Direct
L27 domain0Direct
ADC-like0Direct
Smc hinge domain0Direct
RuvA domain 2-like0Direct
4Fe-4S ferredoxins0Direct
ARID-like0.01314Inherited
SET domain0.02177Inherited
Integrin domains0.05093Inherited
Acyl-CoA N-acyltransferases (Nat)0.1441Inherited
Cysteine-rich domain0.1792Inherited
Transcription factor STAT-4 N-domain0.2438Inherited
STAT0.2438Inherited
Bromodomain0.4502Inherited
MIR domain0.6678Inherited
GroEL equatorial domain-like0.7234Inherited
Family A G protein-coupled receptor-like0.9053Inherited
Cysteine proteinases0.9247Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    64268,50044
  • 64268 - PX domain
  • 50044 - SH3-domain
  • 0Direct
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0Direct
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.02816Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.05893Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.07956Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.2438Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.2438Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.2438Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    141072,141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.04263Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.05525Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.08825Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.2438Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.2438Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.7234Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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