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Phenotypic Abnormality (PA): Abnormal oral morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Phenotypic abnormality [HP:0000118] <25>
+ + + + 4:   Abnormality of head or neck [HP:0000152] <2>(87|107) (98|59|37)
+ + + 3:   Abnormality of the head [HP:0000234] <6>(86|105) (97|58|37)
+ + 2:   Abnormality of the face [HP:0000271] <14>(72|88) (83|47|30)
+ 1:   Abnormality of the mouth [HP:0000153] <2>(38|55) (44|30|22)
0:   Abnormal oral morphology [HP:0031816] <6>(36|50) (42|28|21)
- 1:   Abnormal oral cavity morphology [HP:0000163] <14>(29|42) (35|21|15)
- 1:   Abnormal mandible condylar process morphology [HP:3000077] <1>(0|0) (0|0|0)
- 1:   Abnormal mandible coronoid process morphology [HP:3000078](0|0) (0|0|0)
- 1:   Abnormality of inferior alveolar artery [HP:3000054](0|0) (0|0|0)
- 1:   Abnormality of mandibular symphysis [HP:3000079](0|0) (0|0|0)
- 1:   Pierre-Robin sequence [HP:0000201](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
C-terminal, gelsolin-like domain of Sec23/240Direct
Smc hinge domain0Direct
CalX-like0Direct
Fibrinogen coiled-coil and central regions0Direct
Actin depolymerizing proteins0Direct
TB module/8-cys domain0Direct
Helical domain of Sec23/240Direct
Plakin repeat0Direct
Tricorn protease domain 20Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
Zn-finger domain of Sec23/240Direct
Integrin beta tail domain0Direct
Tudor/PWWP/MBT0.0001676Direct
Hect, E3 ligase catalytic domain0.012Inherited
ARID-like0.02443Inherited
Bromodomain0.02526Inherited
SET domain0.04309Inherited
EGF/Laminin0.05225Inherited
Notch domain0.08792Inherited
BRK domain-like0.08792Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.08792Inherited
RNI-like0.1413Inherited
MHC antigen-recognition domain0.207Inherited
SMAD/FHA domain0.2904Inherited
Transcription factor STAT-4 N-domain0.3132Inherited
STAT0.3132Inherited
Homeodomain-like0.3197Inherited
DEATH domain0.431Inherited
MIR domain0.4319Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4462Inherited
4-helical cytokines0.4675Inherited
Ubiquitin-like0.4836Inherited
Fibrinogen C-terminal domain-like0.5001Inherited
Immunoglobulin0.6394Inherited
Intermediate filament protein, coiled coil region0.8546Inherited
Trypsin-like serine proteases0.9412Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Plakin repeat0Direct
beta-sandwich domain of Sec23/240Direct
Integrin beta tail domain0Direct
Smc hinge domain0Direct
XPF/Rad1/Mus81 nuclease0Direct
PWWP domain0Direct
Histone deacetylase, HDAC0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Fibrinogen coiled-coil and central regions0Direct
Integrin beta EGF-like domains0Direct
Clathrin adaptor core protein0Direct
Trunk domain of Sec23/240Direct
Zn-finger domain of Sec23/240Direct
TB module/8-cys domain0Direct
Protein serine/threonine phosphatase0Direct
Interleukin-1 (IL-1)0Direct
CalX-beta domain0Direct
Helical domain of Sec23/240Direct
PHD domain0.001403Inherited
Histone lysine methyltransferases0.008618Inherited
Hect, E3 ligase catalytic domain0.008618Inherited
PX domain0.008682Inherited
ARID domain0.01804Inherited
Bromodomain0.01924Inherited
Fibroblast growth factors (FGF)0.02292Inherited
Laminin-type module0.02792Inherited
SPRY domain0.03636Inherited
Pyrin domain, PYD0.03636Inherited
VWC domain0.05638Inherited
beta-glycanases0.07213Inherited
DIX domain0.07213Inherited
Notch domain0.07213Inherited
BRK domain-like0.07213Inherited
RecA protein-like (ATPase-domain)0.1197Inherited
28-residue LRR0.1197Inherited
T-box0.1234Inherited
PDZ domain0.1635Inherited
Homeodomain0.1673Inherited
GLA-domain0.1819Inherited
MHC antigen-recognition domain0.1831Inherited
STAT DNA-binding domain0.2832Inherited
STAT0.2832Inherited
Clathrin coat assembly domain0.2832Inherited
Transcription factor STAT-4 N-domain0.2832Inherited
MIR domain0.401Inherited
Fibrinogen C-terminal domain-like0.4702Inherited
C1 set domains (antibody constant domain-like)0.7048Inherited
PLC-like (P variant)0.7382Inherited
Intermediate filament protein, coiled coil region0.8404Inherited
Eukaryotic proteases0.8908Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
C-terminal, gelsolin-like domain of Sec23/240Direct
CalX-like0Direct
Smc hinge domain0Direct
Tricorn protease domain 20Direct
Plakin repeat0Direct
Helical domain of Sec23/240Direct
TB module/8-cys domain0Direct
Actin depolymerizing proteins0Direct
Integrin beta tail domain0Direct
Fibrinogen coiled-coil and central regions0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
Zn-finger domain of Sec23/240Direct
Tudor/PWWP/MBT0.00008205Direct
Cytokine0.003197Inherited
Hect, E3 ligase catalytic domain0.007933Inherited
PX domain0.0081Inherited
ARID-like0.017Inherited
Bromodomain0.01763Inherited
SET domain0.03156Inherited
Multidrug efflux transporter AcrB transmembrane domain0.03433Inherited
EGF/Laminin0.03901Inherited
BRK domain-like0.06859Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.06859Inherited
Notch domain0.06859Inherited
RNI-like0.1154Inherited
DPP6 N-terminal domain-like0.1645Inherited
GLA-domain0.1744Inherited
MHC antigen-recognition domain0.1744Inherited
Glycosyl hydrolase domain0.1759Inherited
SMAD/FHA domain0.2523Inherited
Transcription factor STAT-4 N-domain0.2742Inherited
STAT0.2742Inherited
Homeodomain-like0.2805Inherited
DEATH domain0.3881Inherited
MIR domain0.3889Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4033Inherited
4-helical cytokines0.4244Inherited
Ubiquitin-like0.4399Inherited
Fibrinogen C-terminal domain-like0.4567Inherited
Immunoglobulin0.6001Inherited
Intermediate filament protein, coiled coil region0.8228Inherited
Trypsin-like serine proteases0.9151Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    57581,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0Direct
    64268,50044
  • 64268 - PX domain
  • 50044 - SH3-domain
  • 0Direct
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.017Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.04103Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.06437Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.06859Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1645Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.1744Inherited
    51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0.1759Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.2742Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.2742Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.2742Inherited
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0.2742Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.3069Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.546Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57581,57184
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0Direct
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0Direct
    141072,141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    57581,57184,57581
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.06859Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.07069Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.2742Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.2742Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.3891Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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