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Phenotypic Abnormality (PA): Neoplasm of the thyroid gland

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Neoplasm [HP:0002664] <2>(20|24) (24|8|3)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the thyroid gland [HP:0000820] <2>(8|7) (8|3|0)
+ + 2:   Neoplasm by anatomical site [HP:0011793] <24>(18|21) (21|7|2)
+ + 2:   Abnormality of the endocrine system [HP:0000818] <16>(30|34) (35|12|5)
+ 1:   Neoplasm of the endocrine system [HP:0100568] <6>(6|5) (6|3|0)
+ 1:   Abnormality of thyroid morphology [HP:0011772] <8>(7|6) (7|3|0)
0:   Neoplasm of the thyroid gland [HP:0100031] <2>(6|5) (6|3|0)
- 1:   Thyroid carcinoma [HP:0002890] <5>(0|0) (0|0|0)
- 1:   Thyroid adenoma [HP:0000854] <4>(1|0) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
DNA repair protein MutS, domain III0.000002391Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.000008502Direct
Ribosomal protein S5 domain 2-like0.0001477Direct
Sema domain0.0001982Direct
Plexin repeat0.000852Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.08446Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
DNA gyrase/MutL, second domain0.00000003836Direct
DNA gyrase/MutL, N-terminal domain0.00000003836Direct
DNA repair protein MutS, domain III0.000001904Direct
Sema domain0.0001682Direct
Plexin repeat0.0007331Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
DNA repair protein MutS, domain III0.000001022Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.000003734Direct
Ribosomal protein S5 domain 2-like0.00007201Direct
Sema domain0.00009831Direct
Plexin repeat0.0004577Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.06571Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.00000001741Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000001022Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.00009831Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)