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Phenotypic Abnormality (PA): Cognitive impairment

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the nervous system [HP:0000707] <4>(147|170) (164|102|45)
+ + 2:   Abnormality of nervous system physiology [HP:0012638] <26>(104|120) (119|81|38)
+ 1:   Abnormality of higher mental function [HP:0011446] <9>(38|46) (42|25|8)
0:   Cognitive impairment [HP:0100543] <3>(4|4) (6|4|0)
- 1:   Mental deterioration [HP:0001268] <5>(0|0) (1|1|0)
- 1:   Memory impairment [HP:0002354] <3>(2|3) (3|1|0)
- 1:   Bradyphrenia [HP:0031843](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Glycosyl hydrolase domain0.0003925Direct
(Trans)glycosidases0.0004398Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.03475Inherited
NagB/RpiA/CoA transferase-like0.07676Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
IF2B-like0Direct
alpha-Amylases, C-terminal beta-sheet domain0Direct
DNA gyrase/MutL, second domain0.0004539Direct
DNA gyrase/MutL, N-terminal domain0.0004539Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Glycosyl hydrolase domain0.0002017Direct
(Trans)glycosidases0.0002271Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.02498Inherited
NagB/RpiA/CoA transferase-like0.05933Inherited
RNA-binding domain, RBD0.09799Inherited
Ribosomal protein S5 domain 2-like0.1842Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0.0002017Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0003971Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0008013Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.002308Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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