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Mammalian Phenotype (MP): abnormal sex gland morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   reproductive system phenotype [MP:0005389] <2>(38|58) (47|18|6)
+ + 2:   endocrine/exocrine gland phenotype [MP:0005379] <2>(51|81) (55|36|12)
+ 1:   abnormal reproductive system morphology [MP:0002160] <12>(28|46) (37|15|6)
+ 1:   abnormal gland morphology [MP:0002163] <8>(44|71) (50|31|11)
0:   abnormal sex gland morphology [MP:0000653] <5>(20|29) (23|10|2)
- 1:   abnormal female reproductive gland morphology [MP:0013324] <6>(10|15) (11|6|2)
- 1:   abnormal male reproductive gland morphology [MP:0013325] <4>(10|15) (12|4|0)
- 1:   abnormal preputial gland morphology [MP:0013329] <3>(0|0) (0|0|0)
- 1:   absent sex gland [MP:0000654] <1>(1|1) (1|0|0)
- 1:   dilated sex gland [MP:0000655](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Cystine-knot cytokines0.0004091Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0006428Direct
Nuclear receptor ligand-binding domain0.001547Inherited
The spindle assembly checkpoint protein mad20.001573Inherited
E2F-DP heterodimerization region0.02286Inherited
PAZ domain0.02286Inherited
Nucleic acid-binding proteins0.03361Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.03791Inherited
Tudor/PWWP/MBT0.09032Inherited
SMAD/FHA domain0.1132Inherited
SMAD MH1 domain0.2053Inherited
HMG-box0.2421Inherited
LDL receptor-like module0.2777Inherited
STAT0.3133Inherited
Transcription factor STAT-4 N-domain0.3133Inherited
Bcl-2 inhibitors of programmed cell death0.4309Inherited
Homeodomain-like1Inherited
Immunoglobulin1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
Transforming growth factor (TGF)-beta0.00004259Direct
Nuclear receptor ligand-binding domain0.0009026Direct
DNA gyrase/MutL, second domain0.001025Inherited
The spindle assembly checkpoint protein mad20.001025Inherited
DNA gyrase/MutL, N-terminal domain0.001025Inherited
Single strand DNA-binding domain, SSB0.001636Inherited
Nuclear receptor0.002737Inherited
Gonadodropin/Follitropin0.003569Inherited
E2F dimerization segment0.0158Inherited
Cell cycle transcription factor e2f-dp0.0158Inherited
PAZ domain0.0158Inherited
Cysteine-rich DNA binding domain, (DM domain)0.03249Inherited
Tudor domain0.04058Inherited
Extracellular domain of cell surface receptors0.09198Inherited
SMAD domain0.1717Inherited
SMAD MH1 domain0.1717Inherited
HMG-box0.2058Inherited
LDL receptor-like module0.2393Inherited
Short-chain cytokines0.2634Inherited
STAT DNA-binding domain0.2736Inherited
STAT0.2736Inherited
Transcription factor STAT-4 N-domain0.2736Inherited
Bcl-2 inhibitors of programmed cell death0.3889Inherited
Forkhead DNA-binding domain0.678Inherited
I set domains0.8564Inherited
Homeodomain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 tetramerization domain0Direct
Cystine-knot cytokines0.0002143Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0003433Direct
Nuclear receptor ligand-binding domain0.0008674Direct
The spindle assembly checkpoint protein mad20.0008828Direct
PAZ domain0.01516Inherited
E2F-DP heterodimerization region0.01516Inherited
Nucleic acid-binding proteins0.02303Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0262Inherited
Cysteine-rich DNA binding domain, (DM domain)0.03151Inherited
Tudor/PWWP/MBT0.06747Inherited
SMAD/FHA domain0.08682Inherited
SMAD MH1 domain0.1681Inherited
HMG-box0.2024Inherited
4-helical cytokines0.2024Inherited
Ribonuclease H-like0.2243Inherited
LDL receptor-like module0.2358Inherited
STAT0.2693Inherited
Transcription factor STAT-4 N-domain0.2693Inherited
Bcl-2 inhibitors of programmed cell death0.3839Inherited
Immunoglobulin0.9902Inherited
Homeodomain-like0.9997Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.003092Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.01516Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.01713Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.06456Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.2298Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.2693Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.2693Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.2693Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.8191Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.2693Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.2693Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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