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Mammalian Phenotype (MP): abnormal skeletal muscle morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   muscle phenotype [MP:0005369] <2>(49|57) (54|37|28)
+ 1:   abnormal muscle morphology [MP:0002108] <16>(28|31) (31|22|21)
0:   abnormal skeletal muscle morphology [MP:0000759] <25>(15|15) (16|9|5)
- 1:   abnormal hypaxial muscle morphology [MP:0003358] <10>(7|6) (8|4|2)
- 1:   abnormal skeletal muscle fiber morphology [MP:0003084] <7>(3|4) (3|2|2)
- 1:   abnormal masticatory muscle morphology [MP:0004234] <3>(0|0) (0|0|0)
- 1:   abnormal skeletal muscle mass [MP:0004817] <3>(4|4) (4|2|0)
- 1:   abnormal digastric muscle morphology [MP:0013815] <2>(0|0) (0|0|0)
- 1:   abnormal skeletal muscle glycogen level [MP:0014069] <2>(1|0) (1|0|0)
- 1:   abnormal skeletal muscle mechanoreceptor morphology [MP:0000990] <2>(0|0) (0|0|0)
- 1:   skeletal muscle fibrosis [MP:0009419] <2>(0|0) (0|0|0)
- 1:   abnormal hypodermis muscle layer morphology [MP:0011157] <1>(0|0) (0|0|0)
- 1:   abnormal pharyngeal muscle morphology [MP:0002253] <1>(0|0) (0|0|0)
- 1:   abnormal tongue muscle morphology [MP:0004136] <1>(1|1) (1|0|0)
- 1:   skeletal muscle degeneration [MP:0009415] <1>(0|0) (0|0|0)
- 1:   skeletal muscle necrosis [MP:0003852] <1>(0|1) (0|2|1)
- 1:   abnormal abdominal muscle morphology [MP:0013857](0|0) (0|0|0)
- 1:   abnormal cremaster muscle morphology [MP:0011833](0|0) (0|0|0)
- 1:   abnormal epaxial muscle morphology [MP:0004248](0|0) (0|0|0)
- 1:   abnormal extraocular muscle morphology [MP:0005247](0|0) (0|0|0)
- 1:   abnormal laryngeal muscle morphology [MP:0002263](0|0) (0|0|0)
- 1:   abnormal skeletal muscle fiber type ratio [MP:0009409](1|0) (1|0|0)
- 1:   absent skeletal muscle [MP:0004846](0|0) (0|0|0)
- 1:   decreased satellite cell number [MP:0003833](1|1) (1|0|0)
- 1:   decreased skeletal muscle fiber density [MP:0009408](0|0) (0|0|0)
- 1:   ectopic skeletal muscle [MP:0010056](0|0) (0|0|0)
- 1:   increased satellite cell number [MP:0000730](0|0) (0|0|0)
- 1:   increased skeletal muscle fiber density [MP:0009407](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Lamin A/C globular tail domain0Direct
SRF-like0.0001774Direct
BPTI-like0.009984Inherited
Thyroglobulin type-1 domain0.03327Inherited
Kazal-type serine protease inhibitors0.04865Inherited
RING/U-box0.07646Inherited
TIMP-like0.08303Inherited
Metalloproteases ("zincins"), catalytic domain0.1835Inherited
B-box zinc-binding domain0.1953Inherited
(Trans)glycosidases0.1953Inherited
HLH, helix-loop-helix DNA-binding domain0.2022Inherited
Homeodomain-like0.228Inherited
Growth factor receptor domain0.2604Inherited
Actin-like ATPase domain0.2901Inherited
Cystine-knot cytokines0.6274Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Lamin A/C globular tail domain0Direct
SRF-like0.00012Direct
ZZ domain0.00357Inherited
Small Kunitz-type inhibitors & BPTI-like toxins0.007961Inherited
Thyroglobulin type-1 domain0.02802Inherited
I set domains0.03372Inherited
EF-hand modules in multidomain proteins0.03992Inherited
Ovomucoid domain III-like0.1144Inherited
Laminin-type module0.1671Inherited
B-box zinc-binding domain0.1671Inherited
HLH, helix-loop-helix DNA-binding domain0.1778Inherited
Homeodomain0.2435Inherited
Paired domain0.2574Inherited
Transforming growth factor (TGF)-beta0.3081Inherited
Growth factor receptor domain0.3416Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Lamin A/C globular tail domain0Direct
SRF-like0.00008908Direct
BPTI-like0.006235Inherited
Thyroglobulin type-1 domain0.02278Inherited
Kazal-type serine protease inhibitors0.03427Inherited
Intermediate filament protein, coiled coil region0.04184Inherited
RING/U-box0.0563Inherited
TIMP-like0.06148Inherited
Metalloproteases ("zincins"), catalytic domain0.1484Inherited
(Trans)glycosidases0.159Inherited
B-box zinc-binding domain0.159Inherited
HLH, helix-loop-helix DNA-binding domain0.1653Inherited
Homeodomain-like0.1892Inherited
Growth factor receptor domain0.2194Inherited
Actin-like ATPase domain0.2474Inherited
Cystine-knot cytokines0.5827Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0Direct
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.0003453Direct
    57184,57610
  • 57184 - Growth factor receptor domain
  • 57610 - Thyroglobulin type-1 domain
  • 0.0008343Direct
    100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0008343Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.003083Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.02278Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.03593Inherited
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.159Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.3067Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.00002935Direct
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.0003453Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.04488Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.06148Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.06177Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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