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Mammalian Phenotype (MP): abnormal somatic sensory system morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
+ + 2:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
+ 1:   abnormal somatic nervous system morphology [MP:0002752] <7>(34|47) (37|25|14)
0:   abnormal somatic sensory system morphology [MP:0000959] <4>(26|38) (29|19|12)
- 1:   abnormal sensory neuron morphology [MP:0000965] <16>(16|28) (19|14|9)
- 1:   abnormal sensory ganglion morphology [MP:0000960] <5>(2|4) (4|2|1)
- 1:   abnormal mechanoreceptor morphology [MP:0000972] <4>(10|12) (10|7|5)
- 1:   abnormal vomeronasal organ morphology [MP:0002243] <3>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Tubby C-terminal domain-like0Direct
GDNF receptor-like0.0008334Direct
Frizzled cysteine-rich domain0.001065Inherited
Notch domain0.002789Inherited
GAF domain-like0.006158Inherited
Orange domain-like0.01107Inherited
E2F-DP heterodimerization region0.01107Inherited
Clc chloride channel0.01742Inherited
HLH, helix-loop-helix DNA-binding domain0.0588Inherited
CBS-domain pair0.07098Inherited
Growth factor receptor domain0.116Inherited
Family A G protein-coupled receptor-like0.1533Inherited
Second domain of FERM0.1628Inherited
HD-domain/PDEase-like0.1686Inherited
Cystine-knot cytokines0.2404Inherited
Cyclin-like0.3027Inherited
Sema domain0.3197Inherited
HMG-box0.3431Inherited
PDZ domain-like0.4125Inherited
Cadherin-like0.4798Inherited
Plexin repeat0.5126Inherited
lambda repressor-like DNA-binding domains0.8028Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.8291Inherited
Nicotinic receptor ligand binding domain-like0.8291Inherited
SH3-domain0.8818Inherited
EGF/Laminin0.9254Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Transcriptional factor tubby, C-terminal domain0Direct
Neurotrophin0Direct
Retinoblastoma tumor suppressor domains0Direct
L domain0.00004055Direct
Paired domain0.0003044Direct
GDNF receptor-like0.0005705Direct
Frizzled cysteine-rich domain0.0008394Direct
Notch domain0.002019Inherited
Growth factor receptor domain0.002374Inherited
Adenylyl and guanylyl cyclase catalytic domain0.004344Inherited
DIX domain0.004636Inherited
GAF domain0.004636Inherited
E2F dimerization segment0.004636Inherited
DEP domain0.007792Inherited
Hairy Orange domain0.008575Inherited
Clc chloride channel0.0138Inherited
Cell cycle transcription factor e2f-dp0.02053Inherited
HLH, helix-loop-helix DNA-binding domain0.04632Inherited
CBS-domain pair0.04906Inherited
cAMP-binding domain0.05957Inherited
Calmodulin-like0.07691Inherited
Rhodopsin-like0.09482Inherited
PDEase0.1201Inherited
Cadherin0.2076Inherited
Motor proteins0.2835Inherited
Sema domain0.2873Inherited
HMG-box0.3086Inherited
POU-specific domain0.3086Inherited
EGF-type module0.3373Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.3756Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.3756Inherited
PDZ domain0.4289Inherited
Extracellular domain of cell surface receptors0.4586Inherited
Plexin repeat0.481Inherited
Nicotinic receptor ligand binding domain-like0.8073Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.8073Inherited
SH3-domain0.8668Inherited
Laminin-type module1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Tubby C-terminal domain-like0Direct
GDNF receptor-like0.000451Direct
Frizzled cysteine-rich domain0.000584Direct
Notch domain0.001612Inherited
Nucleotide cyclase0.0032Inherited
GAF domain-like0.003733Inherited
Orange domain-like0.006971Inherited
E2F-DP heterodimerization region0.006971Inherited
Clc chloride channel0.01135Inherited
HLH, helix-loop-helix DNA-binding domain0.04222Inherited
CBS-domain pair0.05194Inherited
Growth factor receptor domain0.08919Inherited
Family A G protein-coupled receptor-like0.1217Inherited
Second domain of FERM0.1299Inherited
HD-domain/PDEase-like0.1349Inherited
"Winged helix" DNA-binding domain0.2005Inherited
Cystine-knot cytokines0.2008Inherited
Cyclin-like0.2594Inherited
Sema domain0.2756Inherited
HMG-box0.2978Inherited
L domain-like0.3168Inherited
PDZ domain-like0.3655Inherited
Cadherin-like0.4322Inherited
Plexin repeat0.4652Inherited
lambda repressor-like DNA-binding domains0.7681Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.7964Inherited
Nicotinic receptor ligand binding domain-like0.7964Inherited
SH3-domain0.8535Inherited
EGF/Laminin0.901Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00002824Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00002824Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.0006161Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.001612Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.003733Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.003733Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.006971Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.006971Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.00887Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2427Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.2427Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.2756Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.2978Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.2978Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.3645Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.5703Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.5913Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.6484Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.7964Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00002824Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00005036Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0002784Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00131Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.002159Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.003733Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2427Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.2978Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.3655Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.4467Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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